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Test Name:
Voltage-Gated Calcium Channel Antibody Assay
- SBMF No:
45510 - Performance Lab Name:
Quest Diagnostics Nichols Institute - Test Mnemonic:
VGCC AB - ABN:
Required – Not FDA-Approved - CPT Code:
83519 - LOINC Code:
19146-0 - Ref Lab Test No:
34057 - Also Known As:
VGCC Antibody Assay
LEMS Antibody
Lambert-Eaton Myasthenic Syndrome Antibody - Also See:
42239 Paraneoplastic Autoantibody Evaluation - Spec Type:
Serum - Spec Container:
Red top (serum) or Gold top (SST) tube - Pref Vol:
1.0 mL - Min Vol:
0.2 mL - Fasting:
No - Spec Collect:
Routine venipuncture - Spec Process:
Clot 30 minutes
Promptly centrifuge 15 minutes
Immediately transfer serum to separate plastic tube - Spec Store Transport:
Refrigerated - Spec Stability:
8 hours room temperature (20-30°C)
14 days refrigerated (2-8°C)
Frozen (-20°C): Indefinite – Do not use frost-free units that undergo repeated freeze/thaw cycles - Methodology:
Radiobinding Assay - Clinical Significance:
This test is used to diagnose Lambert-Eaton myasthenic syndrome, a paraneoplastic syndrome associated with small-cell lung carcinoma - Reference Range:
VGCC Antibody Assay: <23000 fmol/L - Additional Test Info:
This test was performed using a kit that has not been approved or cleared by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics Nichols Institute, San Juan Capistrano. This test should not be used for diagnosis without confirmation by other medically established means. - Day Run:
Sets up 1 day a week - Time Reported:
Reports in 1 day
This is a sendout test. Please note that turnaround time is defined as the anticipated time from set up day to results release. - Test Type:
IMMUNOLOGY