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Test Name:
Rickettsia typhi IgG Antibody, by IFA
- SBMF No:
45391 - Performance Lab Name:
ARUP Laboratories - Test Mnemonic:
TYPHU G - ABN:
Not required - CPT Code:
86757 - Ref Lab Test No:
0050381 - Also Known As:
Typhus Fever IgG Antibodies - Also See:
45393 – Rickettsia typhi IgG & IgM Antibodies, by IFA
45392 – Rickettsia typhi IgM Antibody, by IFA - Spec Type:
Serum - Spec Container:
Gold top (SST) or red top (serum) tube - Pref Vol:
1.0 mL - Min Vol:
0.5 mL
Pediatric Collection: 0.15 mL - Fasting:
No - Spec Collect:
Routine venipuncture
Parallel testing is preferred
Label samples as: "acute" or "convalescent"
Convalescent samples must be received within 30 days from receipt of acute samples - Spec Process:
Clot 30 minutes
Promptly centrifuge 15 minutes
Immediately transfer serum to separate plastic tube - Spec Store Transport:
Refrigerated - Spec Stability:
After separation from cells:
48 hours room temperature (20-30°C)
2 weeks refrigerated (2-8°C)
1 year frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles - Spec Reject:
Severely lipemic, contaminated, or hemolyzed sample - Methodology:
Indirect Fluorescent Antibody (IFA) - Use:
Acute and convalescent titers are often necessary to document disease - Clinical Significance:
Refer to:
- Reference Range:
Rickettsia typhi (Typhus Fever) IgG Antibody, by IFA < 1:64 Negative No significant level of Rickettsia typhi IgG antibody detected. 1:64 - 1:128 Equivocal Questionable presence of Rickettsia typhi IgG antibody detected. Repeat testing in 10-14 days may be helpful. ≥ 1:256 Positive Presence of IgG antibody to Rickettsia typhi detected, suggestive of current or past infection. - Additional Test Info:
This test is for antibodies to Rickettsia typhi. Any antibody reactivity to Rickettsia typhi antigen should, however, also be considered group-reactive for the Typhus Fever group (Rickettsia prowazekii). Seroconversion between acute and convalescent sera is considered strong evidence of recent infection. The best evidence for infection is a significant change (fourfold difference in titer) on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.
- Day Run:
Tue, Fri - Time Reported:
2-6 days - Test Type:
INFECTIOUS ANTIBODY
