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Test Name:
Phenylalanine and Tyrosine, Plasma


  • SBMF No:
    45386
  • Performance Lab Name:
    ARUP Laboratories
  • Test Mnemonic:
    PHE/TYR
  • ABN:
    Not required
  • CPT Code:
    84030; 84510
  • LOINC Code:
    14875-9; 20660-7
  • Ref Lab Test No:
    0080336
  • Test Includes:
    Phenylalanine Monitoring, Plasma
    Tyrosine, Plasma
  • Also Known As:
    PKU monitoring
  • Also See:
    44424 Phenylalanine Monitoring, Plasma
    45385 Tyrosine, Plasma
  • Spec Type:
    Plasma
  • Spec Container:
    Green top (heparin) tube
  • Pref Vol:
    0.5 mL
  • Min Vol:
    Pediatric Collection: 0.25 mL
  • Fasting:
    No
  • Spec Collect:
    Routine venipuncture
  • Spec Process:
    Promptly centrifuge 15 minutes
    Immediately transfer plasma to separate plastic tube and freeze
  • Spec Store Transport:
    Frozen
  • Spec Stability:
    After separation from cells:
    Room temperature (20-30°C): Unacceptable
    24 hours refrigerated (2-8°C)
    1 month frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Spec Reject:
    Hemolyzed sample
  • Spec Remarks:
    Separate plasma from cells ASAP
  • Methodology:
    Ion Exchange Chromatography
  • Use:
    This test is designed to monitor treatment and compliance in PKU patients
  • Reference Range:
    Phenylalanine Monitoring, Plasma
    0-11 months: 30-100 μmol/L
    1 year and older: 30-80 μmol/L
    Tyrosine, Plasma
    0-11 months: 30-140 μmol/L
    1 year and older: 30-120 μmol/L
  • Day Run:
    Mon-Fri
  • Time Reported:
    3-6 days
  • Test Type:
    CHEMISTRY