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Test Name:
Rheumatoid Factor IgA, IgG, and IgM, Serum


  • SBMF No:
    45363
  • Performance Lab Name:
    ARUP Laboratories
  • Test Mnemonic:
    RF PAN
  • ABN:
    Not required
  • CPT Code:
    86430x2; 86431
  • LOINC Code:
    33314-6; 11573-3; 33313-8
  • Ref Lab Test No:
    0051298
  • Test Includes:
    Rheumatoid Factor IgG
    Rheumatoid Factor IgA
    Rheumatoid Factor IgM
  • Also Known As:
    RF Isotypes
    RF3
  • Also See:
    28019 Rheumatoid Factor, Serum
  • Spec Type:
    Serum
  • Spec Container:
    Gold top (SST) or red top (serum) tube
  • Pref Vol:
    1.0 mL
  • Min Vol:
    0.5 mL
  • Fasting:
    No
  • Spec Collect:
    Routine venipuncture
  • Spec Process:
    Clot 30 minutes
    Promptly centrifuge 15 minutes
    Immediately transfer serum to separate plastic tube
  • Spec Store Transport:
    Refrigerated
  • Spec Stability:
    After separation from cells:
    2 days room temperature (20-30°C)
    2 weeks refrigerated (2-8°C)
    Frozen (-20°C): Unacceptable
  • Spec Reject:
    Hemolyzed, lipemic, contaminated, or frozen sample
  • Spec Remarks:
    DO NOT FREEZE
  • Methodology:
    Enzyme-Linked Immunosorbent Assay (ELISA)
  • Clinical Significance:
    Refer to:
    ARUP Consult | The Physician's Guide to Laboratory Test Selection and Interpretation
  • Reference Range:

    Rheumatoid Factor IgA
    Less than 36 U/mL

    Rheumatoid Factor IgG
    Less than 21 U/mL

    Rheumatoid Factor IgM
    Less than 26 IU/mL

    Interpretive Data:
    The presence of abnormal levels of all three rheumatoid factor (RF) isotypes has a specificity of 99% for RA. However, RF in any isotype combination may be found in hepatitis C, Sjögren's syndrome and other chronic infections.

  • Day Run:
    Tue, Thu, Sat
  • Time Reported:
    2-5 days
  • Test Type:
    IMMUNOLOGY