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Test Name:
Rheumatoid Factor IgA, IgG, and IgM, Serum
- SBMF No:
45363 - Performance Lab Name:
ARUP Laboratories - Test Mnemonic:
RF PAN - ABN:
Not required - CPT Code:
86430x2; 86431 - LOINC Code:
33314-6; 11573-3; 33313-8 - Ref Lab Test No:
0051298 - Test Includes:
Rheumatoid Factor IgG
Rheumatoid Factor IgA
Rheumatoid Factor IgM - Also Known As:
RF Isotypes
RF3 - Also See:
28019 Rheumatoid Factor, Serum - Spec Type:
Serum - Spec Container:
Gold top (SST) or red top (serum) tube - Pref Vol:
1.0 mL - Min Vol:
0.5 mL - Fasting:
No - Spec Collect:
Routine venipuncture - Spec Process:
Clot 30 minutes
Promptly centrifuge 15 minutes
Immediately transfer serum to separate plastic tube - Spec Store Transport:
Refrigerated - Spec Stability:
After separation from cells:
2 days room temperature (20-30°C)
2 weeks refrigerated (2-8°C)
Frozen (-20°C): Unacceptable - Spec Reject:
Hemolyzed, lipemic, contaminated, or frozen sample - Spec Remarks:
DO NOT FREEZE - Methodology:
Enzyme-Linked Immunosorbent Assay (ELISA) - Clinical Significance:
Refer to:
- Reference Range:
Rheumatoid Factor IgA
Less than 36 U/mLRheumatoid Factor IgG
Less than 21 U/mLRheumatoid Factor IgM
Less than 26 IU/mLInterpretive Data:
The presence of abnormal levels of all three rheumatoid factor (RF) isotypes has a specificity of 99% for RA. However, RF in any isotype combination may be found in hepatitis C, Sjögren's syndrome and other chronic infections. - Day Run:
Tue, Thu, Sat - Time Reported:
2-5 days - Test Type:
IMMUNOLOGY