South Bend Medical Foundation - Your Community Laboratory

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Test Name:
Quetiapine, Serum or Plasma

• SBMF No:
  45104
• Performance Lab Name:
  ARUP Laboratories
• Test Mnemonic:
  SEROQUEL
• ABN:
  Not required
• CPT Code:
  80299
• LOINC Code:
  19146-0
• Ref Lab Test No:
  2003118
• Also Known As:
  Seroquel®
• Spec Type:
  Serum
• Spec Container:
  Red top (serum) tube
• Alt Spec Type:
  Plasma
• Alt Spec Container:
  Lavender top (EDTA) tube or green top (heparin) tube
• Pref Vol:
  1.0 mL
• Min Vol:
  0.5 mL
• Fasting:
  No
• Patient Prep:
  Trough draws (Immediately prior to dose) preferred
  Peak draws (1.5 hours post dose) NOT recommended
• Spec Collect:
  Do not use gel-barrier tubes for specimen collection
  Routine venipuncture
• Spec Process:
  Serum sample tubes, clot 30 minutes
  Promptly centrifuge 15 minutes
  Immediately transfer serum or plasma to separate plastic tube
• Spec Store Transport:
  Refrigerated
• Spec Stability:
  1 week room temperature (20-30°C)
  1 month refrigerated (2-8°C)
  1 month frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
• Spec Reject:
  Sample collected in gel-barrier tube
• Methodology:
  Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)
• Use:
  Therapeutic Drug Monitoring
• Clinical Significance:
  Refer to:
  
• Reference Range:
  

  Interpretive Data:
  The following therapeutic ranges and critical values have been suggested, but not validated.

  Trough Draws (Preferred)
  Therapeutic range: 70-170 ng/ml
  Critical value: Greater than 1000 ng/mL

  Peak Draws (At 1.5 hour post dose, NOT recommended)
  Therapeutic range: 100-1000 ng/mL
  Critical value: Greater than 1500 ng/mL

• Day Run:
  Tue, Fri
• Time Reported:
  2-6 days
• Test Type:
  TOX-TDM