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Test Name:
Diazepam and Nordiazepam, Serum or Plasma

• SBMF No:
  44964
• Performance Lab Name:
  ARUP Laboratories
• Test Mnemonic:
  DIAZ SP
• ABN:
  Not required
• CPT Code:
  80154
• LOINC Code:
  3548-5; 3537-8
• Ref Lab Test No:
  0090076
• Test Includes:
  Diazepam
  Nordiazepam
• Also Known As:
  Diastat, Diazemuls, Diazepam & Metabolite, Nordiazepam, Stesolid, T-Quil, Valium, Valrelase, Zetran
• Spec Type:
  Serum
• Spec Container:
  Red top (serum) tube
• Alt Spec Type:
  Plasma
• Alt Spec Container:
  Lavender top (EDTA) tube, green top (sodium heparin) tube or gray top (fluoride/oxalate) tube
• Pref Vol:
  1.0 mL
• Min Vol:
  0.5 mL
• Fasting:
  No
• Spec Collect:
  Do not use gel-barrier tubes for specimen collection
  Routine venipuncture
• Spec Process:
  Serum sample tubes, clot 30 minutes
  Promptly centrifuge 15 minutes
  Immediately transfer serum or plasma to separate plastic tube
• Spec Store Transport:
  Refrigerated
• Spec Stability:
  After separation from cells:
  1 week room temperature (20-30°C)
  1 week refrigerated (2-8°C)
  2 months frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
• Spec Reject:
  Sample collected in gel-barrier tube
• Methodology:
  Gas Chromatography (GC)
• Use:
  Therpaeutic Drug Monitoring
• Reference Range:
  

  Diazepam
  0.2-1.0 µg/mL - Based on normal dosage amounts

  Nordiazepam
  0.06-1.80 µg/mL - Based on normal dosage amounts

• Critical High Value:
  Nordiazepam: Toxic: Greater than 2.50 µg/mL
• Day Run:
  Sun-Sat (daily)
• Time Reported:
  2-3 days
• Test Type:
  TOX-TDM