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Test Name:
Fibrinogen Antigen


  • SBMF No:
    44944
  • Performance Lab Name:
    ARUP Laboratories
  • Test Mnemonic:
    FIBAG
  • ABN:
    Not required
  • CPT Code:
    85385
  • LOINC Code:
    3256-5
  • Ref Lab Test No:
    0030135
  • Also See:
    25223 Fibrinogen
  • Spec Type:
    Platelet-poor plasma (PPP)
  • Spec Container:
    Light blue top (3.2% buffered sodium citrate) tube
  • Pref Vol:
    2.0 mL
  • Min Vol:
    1.0 mL
  • Fasting:
    No
  • Patient Prep:
    Collect prior to initiation of anticoagulant therapy
  • Spec Collect:
    Routine venipuncture
    NOTE: Traumatic puncture invalidates sample for coagulation studies and necessitates recollection
    • Observe proper collection order for coagulation tests; collect tubes for coagulation studies prior to collecting tubes containing clot activators, additives, or anticoagulants
    • Fill light blue top tube to stated tube volume
    • If coagulation study is only test ordered, collect 1.0 to 2.0 mL blood into tube for discard, then collect light blue top coagulation study tube(s)
    • If multiple coagulation studies are requested, submit additional samples for each coagulation test
    • Immediately after collection, gently invert tube to mix
  • Spec Process:
    Separate plasma from cells immediately
    • Promptly centrifuge 15 minutes
    • Carefully transfer plasma portion of sample to separate plastic tube using plastic pipette
    NOTE: Buffy coat layer of sample must be avoided
    • Centrifuge transferred plasma sample again to produce platelet-poor plasma (PPP)
    • Use second plastic pipette to carefully transfer PPP sample into plastic aliquot tubes
    • Immediately freeze PPP samples
  • Spec Store Transport:
    Frozen
  • Spec Stability:
    8 hours room temperature (20-30°C)
    24 hours refrigerated (2-8°C)
    1 month frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Spec Reject:
    Citrate tube underfilled
    Sample clotted or hemolyzed
    Non-frozen sample
  • Spec Remarks:
    Platelet-poor plasma (PPP) samples obtained by double centrifugation are critical for accurate coagulation studies as platelet contamination may cause spurious results
  • Methodology:
    Radial Immunodiffusion
  • Clinical Significance:
    Refer to:
    ARUP Consult | The Physician's Guide to Laboratory Test Selection and Interpretation
  • Reference Range:
    149-353 mg/dL
  • Day Run:
    Sun-Sat (daily)
  • Time Reported:
    3-5 days
  • Test Type:
    COAGULATION