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Test Name:
Renin, Direct, Plasma


  • SBMF No:
    44783
  • Performance Lab Name:
    ARUP Laboratories
  • Test Mnemonic:
    RENIN D
  • ABN:
    Not required
  • CPT Code:
    84244
  • LOINC Code:
    2915-7
  • Ref Lab Test No:
    2001575
  • Also Known As:
    Direct Renin
  • Also See:
    30073 Renin Activity, Plasma
    30074 Aldosterone/Renin Activity Ratio
  • Spec Type:
    Plasma
  • Spec Container:
    Lavender top (EDTA) tube
  • Pref Vol:
    2.0 mL
  • Min Vol:
    1.0 mL
  • Fasting:
    No
  • Patient Prep:
    Normal sodium diet (100-200 mEq/day) for at least three days
    Take no medications known to affect renin-aldosterone system
    Contact Medical Director if more information is needed
  • Spec Collect:
    Supine: Specimen should be obtained between 8 a.m. and 10 a.m. (after at least two hours in supine position)
    Upright: Specimen should be obtained before noon (after at least two hours in upright position; seated or standing)
    Routine venipuncture
    Do not collect in refrigerated tubes
  • Spec Process:
    Promptly centrifuge 15 minutes
    Immediately transfer plasma to separate plastic tube and freeze
  • Spec Store Transport:
    Frozen
  • Spec Stability:
    After separation from cells:
    4 hours room temperature (20-30°C)
    Refrigerated (2-8°C): Unacceptable
    4 weeks frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Spec Reject:
    Serum, heparin, citrate or oxalate plasma sample
    Refrigerated sample
    Hemolyzed sample
  • Spec Remarks:
    CRITICAL FROZEN – Separate samples must be submitted when multiple tests are ordered
    Do not refrigerate
    Separate plasma from cells ASAP and freeze immediately
  • Methodology:
    Immunoradiometric Assay
  • Clinical Significance:
    Refer to:
    ARUP Consult | The Physician's Guide to Laboratory Test Selection and Interpretation
  • Reference Range:

    2.5-45.7 pg/mL

    Note:
    Do not use this test for patients treated with Cathepsin B

  • Day Run:
    Mon
  • Time Reported:
    2-9 days
  • Test Type:
    ENZYME