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Test Name:
Neisseria meningitidis Tetravalent IgG Antibodies (Serogroups A, C, W-135, and Y)
- SBMF No:
44778 - Performance Lab Name:
ARUP Laboratories - Test Mnemonic:
NMENING - ABN:
Not required - CPT Code:
86741x4 - LOINC Code:
19146-0; 19146-0; 19146-0; 19146-0 - Ref Lab Test No:
2001603 - Also Known As:
Neisseria meningitidis IgG
Neisseria meningitidis vaccine response - Spec Type:
Serum - Spec Container:
Gold top (SST) or Red top (serum) tube - Pref Vol:
1.0 mL - Min Vol:
0.2 mL - Fasting:
No - Spec Collect:
Routine venipuncture - Spec Process:
Clot 30 minutes
Promptly centrifuge 15 minutes
Immediately transfer serum to separate plastic tube - Spec Store Transport:
Refrigerated - Spec Stability:
After separation from cells:
2 days room temperature (20-30°C)
2 weeks refrigerated (2-8°C)
1 year frozen (-20°) – Do not use frost-free units that undergo repeated freeze/thaw cycles - Methodology:
Quantitative Multi-Analyte Fluorescent Detection (MAFD) - Clinical Significance:
Refer to:
- Reference Range:
N. meningitidis A, C, W-135, Y, IgG:
0.9 µg/mL or less: Antibody concentration not protective.
1.0-2.0 µg/mL: Equivocal.
2.1 µg/mL or greater: Antibody to Neisseria meningitidis detected. Suggestive of protection.Responder status is determined according to the ratio of the one month post-vaccination concentration to pre-vaccination concentration of IgG antibodies to N. meningitidis (Types A, C, Y, and W-135) as follows:
1. If the one month post-vaccination concentration is less than 3.0 µg/mL, the patient is considered to be a non-responder.
2. If the one month post-vaccination concentration is greater than or equal to 3.0 µg/mL, a patient with a ratio of greater than or equal to 4 is a good responder, a ratio of 2-4 is a weak responder, and a ratio of less than 2 is considered a non-responder. - Day Run:
Mon - Time Reported:
2-9 days - Test Type:
INFECTIOUS ANTIBODY
