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Test Name:
Des-gamma-carboxy Prothrombin


  • SBMF No:
    44742
  • Performance Lab Name:
    ARUP Laboratories
  • Test Mnemonic:
    DCP
  • ABN:
    Not required
  • CPT Code:
    83951
  • Ref Lab Test No:
    0081312
  • Also Known As:
    DCP
    PIVKA-II (Protein induced by vitamin K absence or antagonist II)
  • Also See:
    44743 Alpha Fetoprotein, Total & L3 Percent
    44744 Hepatocellular Carcinoma Tumor Marker Panel
  • Spec Type:
    Serum
  • Spec Container:
    Gold top (SST) or red top (serum) tube
  • Pref Vol:
    1.0 mL
  • Min Vol:
    0.5 mL
  • Fasting:
    No
  • Spec Collect:
    Routine venipuncture
  • Spec Process:
    Clot 30 minutes
    Promptly centrifuge 15 minutes
    Immediately transfer serum to separate plastic tube
  • Spec Store Transport:
    Refrigerated
  • Spec Stability:
    After separation from cells:
    8 hours room temperature (20-30°C)
    1 week refrigerated (2-8°C)
    3 months frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Spec Reject:
    Plasma specimen
  • Spec Remarks:
    Separate serum from cells ASAP or within 2 hours of collection
  • Methodology:
    Quantitative Liquid-Phase Binding Immunoassay
  • Clinical Significance:
    Refer to:
    ARUP Consult | The Physician's Guide to Laboratory Test Selection and Interpretation
  • Reference Range:

    By report

    Interpretive Data:
    The µTASWako method is used. Results obtained with different assay methods or kits cannot be used interchangeably. The des-gamma-carboxy prothrombin (DCP) assay is intended as a risk assessment for the development of hepatocellular carcinoma in patients with chronic liver diseases. Elevated DCP values have been shown to be associated with an increased risk for developing hepatocellular carcinoma. Patients with elevated serum DCP should be more intensely evaluated for evidence of hepatocellular carcinoma.

  • Day Run:
    Tue
  • Time Reported:
    2-9 days
  • Test Type:
    TUMOR MARKER