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Test Name:
Estradiol, Ultrasensitive, Serum or Plasma


  • SBMF No:
    44729
  • Performance Lab Name:
    ARUP Laboratories
  • Test Mnemonic:
    ESDIOL TMS
  • ABN:
    Not required
  • CPT Code:
    82670
  • LOINC Code:
    35384-7
  • Ref Lab Test No:
    0093247
  • Also See:
    30085 Estradiol, Serum
  • Spec Type:
    Serum or plasma
  • Spec Container:
    Gold top (SST), Red top (serum), Lavender top (EDTA), or Green top (heparin) tube
  • Pref Vol:
    0.5 mL
  • Min Vol:
    0.3 mL
  • Fasting:
    No
  • Spec Collect:
    Routine venipuncture
  • Spec Process:
    Serum sample tubes, clot 30 minutes
    Promptly centrifuge 15 minutes
    Immediately transfer serum or plasma to separate plastic tube
    Indicate age and sex of patient on test request form AND specimen tube
  • Spec Store Transport:
    Refrigerated
  • Spec Stability:
    After separation from cells:
    48 hours room temperature (20-30°C)
    1 week refrigerated (2-8°C)
    1 month frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Spec Remarks:
    Separate serum or plasma from cells within 2 hours of collection
  • Methodology:
    Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
  • Clinical Significance:
    Refer to:
    ARUP Consult | The Physician's Guide to Laboratory Test Selection and Interpretation
  • Reference Range:
    Estradiol - Children
    Tanner Stages  MalesFemales

    I
    II
    III
    IV and V
    less than 8 pg/mL
    less than 10 pg/mL  
    1-35 pg/mL
    3-35 pg/mL
    less than 56 pg/mL
    2-133 pg/mL
    12-277 pg/mL
    2-259 pg/mL
     
    Age GroupMalesFemales

    7-9
    10-12
    13-15
    16-17
    less than 7 pg/mL
    less than 11 pg/mL
    1-36 pg/mL
    3-34 pg/mL
    less than 36 pg/mL
    1-87 pg/mL
    9-249 pg/mL
    2-266 pg/mL

    Estradiol – Adults
    Females 18 Years and Older  Males 18 Years and Older

    Pre-menopausal:
     Early Follicular: 30-100 pg/mL  
     Late Follicular: 100-400 pg/mL  
     Luteal: 50-150 pg/mL  
    Postmenopausal: 2-21 pg/mL  
    10-42 pg/mL
  • Day Run:
    Sun-Sat (daily)
  • Time Reported:
    2-5 days
  • Test Type:
    HORMONE