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Test Name:
Allergen, Epidermal/Animal Protein, Chicken Feathers IgE
- SBMF No:
44718 - Performance Lab Name:
ARUP Laboratories - Test Mnemonic:
CHICKFEATH - ABN:
May be required – Medical Necessity - CPT Code:
86003 - LOINC Code:
6070-7 - Ref Lab Test No:
0055378 - Also Known As:
Chicken feathers Specific IgE, ImmunoCAP™ e85
Gallus domesticus
Common names: Chicken, Hen, Cock, Cockerel - Also See:
28549 Allergens, Feathers Multiallergen Assay, Qualitative - Spec Type:
Serum - Spec Container:
Gold top (SST) or red top (serum) tube - Pref Vol:
0.25 mL for one allergen, AND
0.1 mL for each allergen ordered - Min Vol:
0.25 mL for one allergen, AND
0.04 mL for each allergen ordered - Fasting:
No - Spec Collect:
Routine venipuncture - Spec Process:
Clot 30 minutes
Promptly centrifuge 15 minutes
Immediately transfer serum to separate plastic tube - Spec Store Transport:
Refrigerated - Spec Stability:
After separation from cells:
48 hours room temperature (20-30°C)
2 weeks refrigerated (2-8°C)
1 year frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles - Spec Reject:
Hemolyzed, icteric, or lipemic sample - Methodology:
ImmunoCAP™ Fluorescent Enzyme Immunoassay (FEIA) - Use:
Detection of allergen-specific IgE antibody - Clinical Significance:
Allergy and diseases caused or complicated by allergy, such as asthma or diseases with symptoms that mimic allergy, are among the most widespread and costly health problems in the world. Traditionally, allergy testing was performed by applying allergens directly to or under the skin. The subsequent appearance of a raised welt indicated sensitivity. However, skin testing carried the risk of serious allergic reaction and was not recommended for young children and or elderly patients.
Although many patients continue to undergo skin (scratch) testing, testing of blood samples for allergen antibodies has been recognized as a viable alternative. Blood testing decreases discomfort for patients and can be performed on patients of all ages, including infants and the elderly. Test results aid in distinguishing allergies from other conditions with similar symptoms, such as colds and other respiratory infections.
Blood allergen testing determines an individual's sensitivity to a given allergen. The test measures IgE (immunoglobulin E), an antibody circulating in the blood when the body is fighting an allergen. Quantitation of blood antibodies is indicator of a patient's sensitivity to a specific allergen. Results are reported in kU/L.
Testing is available for individual allergens or for multi-allergen mixes. Multi-allergen tests do not identify the specific allergen(s) within the mix that may be responsible for a positive result, but do assist with narrowing the search for causative allergic stimuli.
Blood testing can be ordered by the patient's primary care physician or by an allergy specialist. Test results should always be evaluated in combination with a thorough patient history and physical.
Additional information available online at phadia.com.
- Reference Range:
Less than 0.10 kU/L: No significant level detected
0.10-0.34 kU/L: Clinical relevance undetermined
0.35-0.70 kU/L: Low
0.71-3.50 kU/L: Moderate
3.51-17.50 kU/L: High
17.51 kU/L or Greater: Very HighInterpretive Data:
Allergen results of 0.10-0.34 kU/L are intended for specialist use as the clinical relevance is undetermined. Although increasing ranges are reflective of increasing concentrations of allergen-specific IgE, this may not correlate with the degree of clinical response or skin testing when challenged with a specific allergen. The correlation of allergy laboratory results with clinical history and in vivo reactivity to specific allergens is essential. A negative test may not rule out clinical allergy or even anaphylaxis. - Day Run:
Sun-Sat (daily) - Time Reported:
2-3 days - Test Type:
ALLERGENS
