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Test Name:
Varicella-Zoster Virus IgG Antibody, Cerebrospinal Fluid


  • SBMF No:
    44668
  • Performance Lab Name:
    ARUP Laboratories
  • Test Mnemonic:
    CSF VZV G
  • ABN:
    Not required
  • CPT Code:
    86787
  • LOINC Code:
    58755-0
  • Ref Lab Test No:
    0054444
  • Also See:
    44516 Varicella-Zoster Virus by PCR
  • Spec Type:
    Cerebrospinal fluid (CSF)
  • Spec Container:
    Plastic transport tube with threaded cap
  • Pref Vol:
    0.5 mL
  • Min Vol:
    0.3 mL
  • Spec Collect:
    Collected by physician
  • Spec Store Transport:
    Refrigerated
  • Spec Stability:
    8 hours room temperature (20-30°C)
    2 weeks refrigerated (2-8°C)
    1 year frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Spec Reject:
    Heat-inactivated or contaminated sample
  • Spec Remarks:
    CSF is the only acceptable sample type
  • Methodology:
    Enzyme-Linked Immunosorbent Assay (ELISA)
  • Clinical Significance:
    Refer to:
    ARUP Consult | The Physician's Guide to Laboratory Test Selection and Interpretation
  • Reference Range:

    0.89 IV or less: Negative - No significant level of IgG antibody to varicella-zoster virus detected.
    0.90-1.09 IV: Equivocal - Repeat testing in 10-14 days may be helpful.
    1.10 IV or greater: Positive - IgG antibody to varicella-zoster virus detected, which may indicate a current or past infection.

    Interpretive Data:
    The detection of antibodies to varicella-zoster in CSF may indicate central nervous system infection. However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier.

  • Additional Test Info:
    The manufacturer has not determined the efficacy of this test when performed on CSF specimens. The performance characteristics of this test were determined by ARUP laboratories.
  • Day Run:
    Sun, Tue-Sat
  • Time Reported:
    1-2 days
  • Test Type:
    INFECTIOUS ANTIBODY