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Test Name:
Dengue Fever Virus IgM Antibody
- SBMF No:
44625 - Performance Lab Name:
ARUP Laboratories - Test Mnemonic:
DEN M - ABN:
Required – Not FDA-Approved - CPT Code:
86790 - LOINC Code:
23992-1 - Ref Lab Test No:
0093098 - Also Known As:
Breakbone fever
Flavivirus
Hemorrhagic fever - Also See:
44626 Dengue Fever Virus IgG and IgM Antibodies - Spec Type:
Serum - Spec Container:
Gold top (SST) or red top (serum) tube - Pref Vol:
1.0 mL - Min Vol:
0.1 mL - Fasting:
No - Spec Collect:
Routine venipuncture
Parallel testing is preferred
Label samples as: "acute" or "convalescent"
Convalescent samples must be received within 30 days from receipt of acute samples - Spec Process:
Clot 30 minutes
Promptly centrifuge 15 minutes
Immediately transfer serum to separate plastic tube - Spec Store Transport:
Refrigerated - Spec Stability:
After separation from cells:
48 hours room temperature (20-30°C)
2 weeks refrigerated (2-8°C)
1 year frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles - Spec Reject:
Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimen - Spec Remarks:
Separate serum from cells ASAP or within 2 hours of collection - Methodology:
Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA) - Clinical Significance:
Refer to:
- Reference Range:
1.64 IV or less: Negative - No significant level of detectable dengue fever virus IgM antibody.
1.65-2.84 IV: Equivocal - Questionable presence of antibodies. Repeat testing in 10-14 days may be helpful.
2.85 IV or greater: Positive - IgM antibody to dengue fever virus detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.Interpretive Data:
The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time. - Additional Test Info:
This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. - Day Run:
Mon - Time Reported:
2-9 days - Test Type:
INFECTIOUS ANTIBODY
