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Test Name:
Dengue Fever Virus IgG Antibody
- SBMF No:
44624 - Performance Lab Name:
ARUP Laboratories - Test Mnemonic:
DEN G - ABN:
Required – Not FDA-Approved - CPT Code:
86790 - Ref Lab Test No:
0093097 - Also Known As:
Breakbone fever
Flavivirus
Hemorrhagic fever - Also See:
44626 Dengue Fever Virus IgG and IgM Antibodies - Spec Type:
Serum - Spec Container:
Gold top (SST) or red top (serum) tube - Pref Vol:
1.0 mL - Min Vol:
0.1 mL - Fasting:
No - Spec Collect:
Routine venipuncture
Parallel testing is preferred
Label samples as: "acute" or "convalescent"
Convalescent samples must be received within 30 days from receipt of acute samples - Spec Process:
Clot 30 minutes
Promptly centrifuge 15 minutes
Immediately transfer serum to separate plastic tube - Spec Store Transport:
Refrigerated - Spec Stability:
After separation from cells:
48 hours room temperature (20-30°C)
2 weeks refrigerated (2-8°C)
1 year frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles - Spec Reject:
Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimen - Spec Remarks:
Separate serum from cells ASAP or within 2 hours of collection - Methodology:
Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA) - Clinical Significance:
Refer to:
- Reference Range:
1.64 IV or less: Negative - No significant level of detectable dengue fever virus IgG antibody.
1.65-2.84 IV: Equivocal - Questionable presence of antibodies. Repeat testing in 10-14 days may be helpful.
2.85 IV or greater: Positive - IgG antibody to dengue fever virus detected, which may indicate a current or past infection.Interpretive Data:
Patients in the early stage of dengue fever virus infection may not have detectable IgG antibodies, as the IgG response may take several weeks to develop. In the absence of detectable IgG, testing for IgM class antibody is strongly recommended. The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time. - Additional Test Info:
This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. - Day Run:
Mon - Time Reported:
2-9 days - Test Type:
INFECTIOUS ANTIBODY
