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Test Name:
Sertraline, Serum or Plasma
- SBMF No:
44570 - Performance Lab Name:
ARUP Laboratories - Test Mnemonic:
SERT- - ABN:
Not required - CPT Code:
80299 - LOINC Code:
6906-2 - Ref Lab Test No:
0098745 - Also Known As:
Lustral
Zoloft - Spec Type:
Serum - Spec Container:
Red top (serum) tube - Alt Spec Type:
Plasma - Alt Spec Container:
Lavender top (EDTA), green top (sodium heparin), or gray top (fluoride/oxalate) tube - Pref Vol:
2.0 mL - Min Vol:
1.5 mL - Fasting:
No - Spec Collect:
Do not use gel-barrier tubes for specimen collection
Routine venipuncture - Spec Process:
Serum sample tubes, clot 30 minutes
Promptly centrifuge 15 minutes
Immediately transfer serum or plasma to separate plastic tube - Spec Store Transport:
Refrigerated - Spec Stability:
After separation from cells:
12 hours room temperature (20-30°C)
4 days refrigerated (2-8°C)
1 month frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles - Methodology:
Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS) - Reference Range:
Therapeutic Range: Not well established
Interpretive Data:
No therapeutic range exists for sertraline. Dosing should begin at 50 mg/d, not to exceed 200 mg/d. Dosing above 200 mg/d is associated with increased adverse effects and decreased efficacy. Dosing of 50-200 mg/d gives serum values ranging from 30-200 ng/mL. - Day Run:
Tue, Fri - Time Reported:
2-6 days - Test Type:
TOX-TDM
