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Test Name:
Neuron Specific Enolase, Serum


  • SBMF No:
    44565
  • Performance Lab Name:
    ARUP Laboratories
  • Test Mnemonic:
    NSE-
  • ABN:
    Required – Not FDA-Approved
  • CPT Code:
    86316
  • LOINC Code:
    15060-7
  • Ref Lab Test No:
    0098198
  • Also Known As:
    NSE
  • Spec Type:
    Serum
  • Spec Container:
    Red top (serum) tube
  • Pref Vol:
    1.0 mL
  • Min Vol:
    0.5 mL
  • Fasting:
    No
  • Spec Collect:
    Do not use gel-barrier tubes for specimen collection
    Routine venipuncture
  • Spec Process:
    Allow blood to clot completely at room temperature
    Promptly centrifuge 15 minutes
    Immediately transfer serum to separate plastic tube and freeze
  • Spec Store Transport:
    Frozen
  • Spec Stability:
    Room temperature (20-30°C): Unacceptable
    24 hours refrigerated (2-8°C)
    1 year frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Spec Reject:
    Plasma
    Hemolyzed sample
  • Spec Remarks:
    Separate serum from cells ASAP
    Serum should be separated from cells immediately to avoid release of NSE from blood cells
  • Methodology:
    Enzyme-Linked Immunosorbent Assay (ELISA)
  • Clinical Significance:
    Refer to:
    ARUP Consult | The Physician's Guide to Laboratory Test Selection and Interpretation
  • Reference Range:
    3.7-8.9 µg/L

    Interpretive Data:
    This assay is performed using the CanAg® Neuron Specific Enolase Enzyme Immunoassay. Results obtained with different assay methods or kits cannot be used interchangeably.

  • Additional Test Info:
    This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
  • Day Run:
    Mon, Wed, Fri
  • Time Reported:
    2-5 days
  • Test Type:
    ENZYME