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Test Name:
Varicella-Zoster Virus, by PCR


  • SBMF No:
    44516
  • Performance Lab Name:
    ARUP Laboratories
  • Test Mnemonic:
    VZVPCR
  • ABN:
    Required – Not FDA-Approved
  • CPT Code:
    87798
  • LOINC Code:
    31208-2; 11483-5
  • Ref Lab Test No:
    0060042
  • Also Known As:
    VZV by PCR
    Chicken Pox Virus by PCR
    Herpes zoster by PCR
    Human Herpesvirus 3 (HHV-3) by PCR
  • Spec Type:
    CSF or ocular specimen
  • Spec Container:
    Sterile container with screw-top cap
  • Alt Spec Type:
    Vesicle fluid or tissue biopsy
  • Alt Spec Container:
    Viral transport media (Microtest M4 or UTM)
  • Pref Vol:
    1.0 mL
  • Min Vol:
    Pediatric Collection: 0.25 mL (Less volume may decrease sensitivity of assay)
  • Spec Collect:
    CSF or ocular sample collected in sterile container
    Vesicle fluid or tissue biopsy collected in viral transport media
    Sample source is required on container and requisition
  • Spec Process:
    Freeze tissue samples immediately
  • Spec Store Transport:
    Frozen
    Submit specimen according to Biological Substance, Category B, shipping guidelines
  • Spec Stability:
    8 hours room temperature (20-30°C) – excludes tissues
    3 days (72 hours) refrigerated (2-8°C) – excludes tissues
    3 months frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Spec Reject:
    Nonsterile or leaking containers
    Heparinized or hemolyzed sample
    Tissue in formalin or other preservatives
  • Methodology:
    Polymerase Chain Reaction (PCR)
  • Clinical Significance:
    Refer to:
    ARUP Consult | The Physician's Guide to Laboratory Test Selection and Interpretation
  • Reference Range:
    Varicella-Zoster Virus, by PCR
    Negative - Varicella-zoster virus DNA not detected by PCR
    Positive - Varicella-zoster virus DNA detected by PCR
    Interpretive Data:
    A negative result does not rule out the presence of PCR inhibitors in the patient specimen or varicella-zoster virus DNA concentrations below the level of detection of the assay.
  • Additional Test Info:

    This test is performed pursuant to an agreement with Roche Molecular Systems, Inc.

    This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

  • Day Run:
    Mon, Wed, Fri
  • Time Reported:
    2-5 days
  • Test Type:
    INFECTIOUS ORGANISM