test directorySearch Results
Click here to search again.
Test Name:
Treponema pallidum IgM Antibody, by ELISA
- SBMF No:
44400 - Performance Lab Name:
ARUP Laboratories - Test Mnemonic:
STS IGM- - ABN:
Required – Not FDA-Approved - CPT Code:
86780 - LOINC Code:
22594-6 - Ref Lab Test No:
0050921 - Also Known As:
Syphilis IgM Antibody - Also See:
28244 Treponema pallidum IgG Antibody, by MFI, with RPR Titer if Indicated - Spec Type:
Serum - Spec Container:
Gold top (SST) or red top (serum) tube - Pref Vol:
1.0 mL - Min Vol:
0.5 mL - Fasting:
No - Spec Collect:
Routine venipuncture - Spec Process:
Clot 30 minutes
Promptly centrifuge 15 minutes
Immediately transfer serum to separate plastic tube - Spec Store Transport:
Refrigerated - Spec Stability:
After separation from cells:
2 days at room temperature (20-30°C)
2 weeks refrigerated (2-8°C)
1 year frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles - Spec Reject:
Severely lipemic, contaminated, or hemolyzed sample
Plasma sample or other body fluid sample - Methodology:
Enzyme-Linked Immunosorbent Assay (ELISA) - Clinical Significance:
Refer to:
- Reference Range:
- Treponema pallidum Antibody, IgM by ELISA
- 0.8 IV or less: Negative – No significant level of Treponema pallidum IgM antibody detected
0.9-1.1 IV: Equivocal – Questionable presence of Treponema pallidum IgM antibody detected. Repeat testing 10-14 days may be helpful
1.2 IV or greater: Positive – Presence of IgM antibody to Treponema pallidum detected, suggestive of current or recent infection - Interpretive Data:
- Seroconversion between acute and convalescent sera is considered strong evidence of recent infection. The best evidence for infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time. IgM testing is a useful diagnostic aid in differentiating between maternally derived IgG antibodies which cross the placenta, from the IgM antibodies of an active infection in the newborn. In IgM testing for congenital syphilis, the sensitivity is 80%. Therefore, a negative IgM does not necessarily rule out the possibility of congenital syphilis.
- Additional Test Info:
This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. - Day Run:
Wed - Time Reported:
2-9 days - Test Type:
INFECTIOUS ANTIBODY
