South Bend Medical Foundation - Your Community Laboratory

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Test Name:
Helicobacter pylori IgA Antibody

• SBMF No:
  44363
• Performance Lab Name:
  ARUP Laboratories
• Test Mnemonic:
  A PYLORI
• ABN:
  Not required
• CPT Code:
  86677
• LOINC Code:
  6420-4
• Ref Lab Test No:
  0050995
• Spec Type:
  Serum
• Spec Container:
  Gold top (SST) or red top (serum) tube
• Alt Spec Type:
  Plasma
• Alt Spec Container:
  Lavender top (EDTA) tube or green top (heparin) tube
• Pref Vol:
  0.5 mL
• Min Vol:
  0.1 mL
• Fasting:
  No
• Spec Collect:
  Routine venipuncture
• Spec Process:
  Serum sample tubes, clot 30 minutes
  Promptly centrifuge 15 minutes
  Immediately transfer serum or plasma to separate plastic tube
• Spec Store Transport:
  Refrigerated
• Spec Stability:
  After separation from cells:
  2 days room temperature (20-30°C)
  2 weeks refrigerated (2-8°C)
  1 year frozen (-20°) – Do not use frost-free units that undergo repeated freeze/thaw cycles
• Spec Reject:
  Severely lipemic, contaminated, heat-inactivated, or hemolyzed sample
• Methodology:
  Enzyme Immunoassay (EIA)
• Clinical Significance:
  Refer to:
  
• Reference Range:
  

  1.7 EV or less: Negative - No significant level of IgA antibody to H. pylori detected
  1.8-2.2 EV: Equivocal - Repeat testing in 10-14 days may be helpful
  2.3 EV or greater: Positive - IgA antibody to H. pylori detected, suggestive of active infection

  Interpretive Data:
  Helicobacter pylori IgG and IgA antibody seroconversion occur together after 60 days. Samples which have a high titer of both IgG and IgA antibodies to H. pylori in symptomatic individuals may be considered to represent an active infection. However, a positive H. pylori IgA result can only suggest active infection and should be confirmed by bacterial isolation and other diagnostic testing.

• Day Run:
  Sun-Sat (daily)
• Time Reported:
  1-2 days
• Test Type:
  INFECTIOUS ANTIBODY