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Test Name:
Erythrocyte Porphyrin, Whole Blood


  • SBMF No:
    44262
  • Performance Lab Name:
    ARUP Laboratories
  • Test Mnemonic:
    FEP
  • ABN:
    Not required
  • CPT Code:
    84202
  • LOINC Code:
    2898-5
  • Ref Lab Test No:
    0020610
  • Also Known As:
    EP
    FEP
    Free Erythrocyte Porphyrin
    Porphyrins, Whole Blood
    Protoporphyrin, Free Erythrocyte
  • Also See:
    44077 Porphyrins, Total, Serum
    23245 Zinc Protoporphyrin, Whole Blood
  • Spec Type:
    Whole blood
  • Spec Container:
    Lavender top (EDTA) tube
  • Alt Spec Type:
    Whole blood
  • Alt Spec Container:
    Dark blue (royal) top (trace metal-free - EDTA) tube
        IMPORTANT: Do not use dark blue (royal) top (trace metal-free - serum) tube
  • Pref Vol:
    1.0 mL
  • Min Vol:
    0.5 mL
  • Fasting:
    No
  • Spec Collect:
    Routine venipuncture
  • Spec Process:
    Gently invert tube to mix blood with the anticoagulant
    Transfer well-mixed whole blood to separate amber plastic tube
  • Spec Store Transport:
    Refrigerated
    Protect from light within one hour of collection and during storage and shipment
  • Spec Stability:
    Room temperature (20-30°C): Unacceptable
    2 weeks refrigerated (2-8°C)
    1 month frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Spec Reject:
    Clotted sample
    Sample not collected in EDTA
  • Spec Remarks:
    Protect from light within one hour of collection and during storage and shipment
    Samples not protected from light are acceptable but reported with a disclaimer
    Use Dark blue (royal) top (trace metal-free - EDTA) tube when also testing for lead.
    Samples should be tested for lead FIRST to avoid potential contamination problems.
  • Methodology:
    Extraction/Fluorometry
  • Clinical Significance:
    Refer to:
    ARUP Consult | The Physician's Guide to Laboratory Test Selection and Interpretation
  • Reference Range:

    0-35 µg/dL

    Note:
    Elevated EP results are seen in early and late iron deficiency, in the anemia of chronic disease, and in chronic lead poisoning (typically when blood lead is greater than 25 µg/dL). Elevated protoporphyrin (as in erythropoietic protoporphyria) and zinc coproporphyrin (usually associated with childbirth) can increase the apparent EP signal. A more specific test for free protoporphyrin is Porphyrins, Total, Serum (44077). Specimens which are hemolyzed, clotted, or improperly aliquoted may show false elevations.

  • Day Run:
    Mon, Wed, Sat
  • Time Reported:
    2-5 days
  • Test Type:
    CHEMISTRY

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