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Test Name:
Treponema pallidum Antibody, by TP-PA
- SBMF No:
44254 - Performance Lab Name:
ARUP Laboratories - Test Mnemonic:
MHA-TP - ABN:
Not required - CPT Code:
86780 - LOINC Code:
24312-1 - Ref Lab Test No:
0050777 - Also Known As:
Syphilis Antibody by MHA
Syphilis Serology
T. pallidum Antibody by MHA (MHA-TP)
TP-PA - Also See:
28244 Treponema pallidum IgG Antibody, by MFI, with RPR Titer if Indicated
28030 Treponema pallidum IgG Antibody (FTA-ABS), Serum - Spec Type:
Serum - Spec Container:
Gold top (SST) or red top (serum) tube - Alt Spec Type:
Plasma - Alt Spec Container:
Light green top (PST) tube or green top (heparin) tube - Pref Vol:
1.0 mL - Min Vol:
0.1 mL - Fasting:
No - Spec Collect:
Routine venipuncture - Spec Process:
Serum sample tubes, clot 30 minutes
Promptly centrifuge 15 minutes
Immediately transfer serum or plasma to separate plastic tube - Spec Store Transport:
Refrigerated - Spec Stability:
After separation from cells:
2 days room temperature (20-30°C)
2 weeks refrigerated (2-8°C)
1 year frozen (-20°) – Do not use frost-free units that undergo repeated freeze/thaw cycles) - Spec Reject:
CSF or other body fluids - Spec Remarks:
Separate serum or plasma from cells ASAP - Methodology:
Semi-Quantitative Particle Agglutination - Clinical Significance:
Refer to:
- Reference Range:
Nonreactive
Note:
TP-PA is a helpful diagnostic aid for the patient with a reactive reagin test, but presents with atypical signs of primary, secondary, or late syphilis. TP-PA compares favorably with the FTA test, but appears slightly less sensitive in cases of untreated early primary syphilis. In late syphilis, the agreement with FTA is 99%.VDRL is the preferred test for cerebrospinal fluid. Treponemal tests (TP-PA or FTA) are not recommended for CSF. FTAs on CSF may be tested, but TP-PA cannot be tested on CSF.
- Day Run:
Mon-Fri - Time Reported:
2-5 days - Test Type:
INFECTIOUS ANTIBODY
