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Test Name:
Islet Cell IgG Antibody
- SBMF No:
44250 - Performance Lab Name:
ARUP Laboratories - Test Mnemonic:
ISLET AB - ABN:
Not required - CPT Code:
86341 - LOINC Code:
13927-9 - Ref Lab Test No:
0050138 - Also Known As:
Anti-Islet Cell Antibody, IgG
ICA
CICA (Cytoplasmic Islet Cell Antibody) - Spec Type:
Serum - Spec Container:
Gold top (SST) or red top (serum) tube - Pref Vol:
1.0 mL - Min Vol:
0.15 mL - Fasting:
No - Spec Collect:
Routine venipuncture - Spec Process:
Clot 30 minutes
Promptly centrifuge 15 minutes
Immediately transfer serum to separate plastic tube - Spec Store Transport:
Refrigerated - Spec Stability:
After separation from cells:
48 hours room temperature (20-30°C)
2 weeks refrigerated (2-8°C)
1 year frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles - Spec Reject:
Plasma sample
Severely lipemic, contaminated, or hemolyzed sample - Spec Remarks:
Separate serum from cells ASAP - Methodology:
Indirect Fluorescent Antibody (IFA) - Clinical Significance:
Refer to:
- Reference Range:
< 1:4 No antibody detected
Interpretive Data:
Islet cell antibodies (ICAs) are associated with type 1 diabetes (T1D), an autoimmune endocrine disorder. These antibodies may be present in individuals years before the onset of clinical symptoms. To calculate Juvenile Diabetes Foundation (JDF) units: multiply the titer x 5 (1:8 8 x 5 = 40 JDF Units). - Day Run:
Mon, Wed, Fri - Time Reported:
2-4 days - Test Type:
IMMUNOLOGY
