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Test Name:
C-1-Esterase Inhibitor, Functional


  • SBMF No:
    44223
  • Performance Lab Name:
    ARUP Laboratories
  • Test Mnemonic:
    C1EST FNC
  • ABN:
    Not required
  • CPT Code:
    86161
  • LOINC Code:
    10634-4
  • Ref Lab Test No:
    0050141
  • Also Known As:
    C1 inactivator, Functional
  • Also See:
    44285 C1-Esterase Inhibitor
  • Spec Type:
    Serum
  • Spec Container:
    Gold top (SST) or red top (serum) tube
  • Alt Spec Type:
    Plasma
  • Alt Spec Container:
    Lavender top (EDTA) tube
  • Pref Vol:
    0.5 mL
  • Min Vol:
    0.1 mL
  • Fasting:
    No
  • Spec Collect:
    Routine venipuncture
  • Spec Process:
    Serum sample tubes, clot 30 minutes
    Promptly centrifuge 15 minutes
    Immediately transfer serum or plasma to separate plastic tube and freeze
  • Spec Store Transport:
    Frozen
  • Spec Stability:
    After separation from cells:
    2 hours room temperature (20-30°C)
    Refrigerated (2-8°C): Unacceptable
    2 weeks frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Spec Reject:
    Non-frozen sample
  • Spec Remarks:
    CRITICAL FROZEN – Separate samples must be submitted when multiple tests are ordered
    Separate serum or plasma from cells and freeze ASAP
  • Methodology:
    Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)
  • Clinical Significance:
    Refer to:
    ARUP Consult | The Physician's Guide to Laboratory Test Selection and Interpretation
  • Reference Range:
    68% or greater: Normal
    41-67%: Indeterminate
    40% or less: Abnormal
  • Day Run:
    Sun, Wed, Fri
  • Time Reported:
    2-5 days
  • Test Type:
    ENZYME