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Test Name:
Risperidone and Metabolite, Serum or Plasma


  • SBMF No:
    44157
  • Performance Lab Name:
    NMS Labs
  • Test Mnemonic:
    RISPERID
  • ABN:
    Not required
  • CPT Code:
    80299
  • LOINC Code:
    19146-0; 19146-0; 19146-0
  • Ref Lab Test No:
    4105SP (ARUP# 0092055)
  • Test Includes:
    Risperidone, 9-Hydroxyrisperidone, Risperidone and 9-Hydroxyrisperidone - Total
  • Also Known As:
    Risperdal®, Risperidone Metabolite, Total Active Moiety
  • Spec Type:
    Serum or plasma
  • Spec Container:

    Red top (serum), Lavender top (EDTA), or Green top (heparin) tube **

    ** NMS Labs has no experimental or literature-based data regarding the choice of specific specimen collection containers for this test

  • Pref Vol:
    1.0 mL
  • Spec Collect:
    Do not use gel-barrier tubes for specimen collection
    Routine venipuncture
  • Spec Process:
    Serum sample tubes, clot 30 minutes
    Promptly centrifuge 15 minutes
    Immediately transfer serum or plasma to separate plastic tube
  • Spec Store Transport:
    Refrigerated
  • Spec Stability:
    14 days room temperature (20-30°C)
    14 days refrigerated (2-8°C)
    7 months frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Spec Reject:
    Specimen collected in polymer gel separation tube (SST or PST)
  • Methodology:
    High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)
  • Use:
    Therapeutic Drug Monitoring
  • Clinical Significance:

    Antipsychotic (Neuroleptic)

    Refer to:
    ARUP Consult | The Physician's Guide to Laboratory Test Selection and Interpretation

  • Reference Range:
    By report
  • Additional Test Info:
    This test is referred through ARUP Laboratories
  • Day Run:
    Varies
  • Time Reported:
    Varies
  • Test Type:
    TOX-TDM