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Test Name:
Calcitonin


  • SBMF No:
    44128
  • Performance Lab Name:
    ARUP Laboratories
  • Test Mnemonic:
    CAL-
  • ABN:
    Not required
  • CPT Code:
    82308
  • LOINC Code:
    1992-7
  • Ref Lab Test No:
    0070006
  • Also Known As:
    Thyrocalcitonin
  • Spec Type:
    Serum or plasma
  • Spec Container:
    Gold top (SST) or Green top (heparin) tube
  • Pref Vol:
    2.0 mL
  • Min Vol:
    1.0 mL
  • Fasting:
    No
  • Spec Collect:
    Routine venipuncture
  • Spec Process:
    Serum sample tubes, clot 30 minutes
    Promptly centrifuge 15 minutes
    Immediately transfer serum or plasma to separate plastic tube
  • Spec Store Transport:
    Refrigerated
  • Spec Stability:
    After separation from cells:
    8 hours room temperature (20-30°C)
    1 week refrigerated (2-8°C)
    3 months frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Spec Reject:
    EDTA plasma
    Grossly hemolyzed or lipemic specimen
  • Spec Remarks:
    Separate serum or plasma from cells ASAP or within 2 hours of collection
  • Methodology:
    Quantitative Chemiluminescent Immunoassay (CLIA)
  • Clinical Significance:
    Refer to:
    ARUP Consult | The Physician's Guide to Laboratory Test Selection and Interpretation
  • Reference Range:

    Male 3 years and older: 0.0-7.5 pg/mL
    Female 3 years and older: 0.0-5.1 pg/mL

    Interpretive Data:
    Calcitonin levels greater than 100 pg/mL may occur in the following conditions: medullary thyroid carcinomas (MTC), leukemias, and myeloproliferative disorders.

    Provocative testing (calcium) is suggested in patients with MTC if the calcitonin is not clearly diagnostic.

    The Siemens Immulite® 2000 method is used. Results obtained with different assay methods or kits cannot be used interchangeably. Calcitonin is useful in monitoring medullary thyroid carcinoma. The calcitonin assay value, regardless of level, should not be interpreted as absolute evidence of the presence or absence of malignant disease.

  • Day Run:
    Sun-Sat (daily)
  • Time Reported:
    2-3 days
  • Test Type:
    TUMOR MARKER