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Test Name:
Saint Louis Encephalitis IgG Antibody, by IFA, Serum


  • SBMF No:
    44060
  • Performance Lab Name:
    ARUP Laboratories
  • Test Mnemonic:
    ST LOUIS
  • ABN:
    Not required
  • CPT Code:
    86653
  • LOINC Code:
    10906-6
  • Ref Lab Test No:
    0050507
  • Also Known As:
    Encephalitis Antibody, St Louis, IgG
    SLE IgG Ab
    St Louis IgG Ab
    St. Louis IgG Ab
  • Also See:
    44056 California Encephalitis IgG Antibody, Serum
    44059 Eastern Equine Encephalitis IgG Antibody, Serum
    28237 West Nile Virus IgG Antibody, Serum
    44061 Western Equine Encephalitis IgG Antibody, Serum
  • Spec Type:
    Serum
  • Spec Container:
    Gold top (SST) or red top (serum) tube
  • Pref Vol:
    1.0 mL
  • Min Vol:
    0.5 mL
    Pediatric Collection: 0.15 mL
  • Fasting:
    No
  • Spec Collect:
    Routine venipuncture
    Parallel testing is preferred
    Label samples as: "acute" or "convalescent"
    Convalescent samples must be received within 30 days from receipt of acute samples
  • Spec Process:
    Clot 30 minutes
    Promptly centrifuge 15 minutes
    Immediately transfer serum to separate plastic tube
  • Spec Store Transport:
    Refrigerated
  • Spec Stability:
    After separation from cells:
    48 hours room temperature (20-30°C)
    2 weeks refrigerated (2-8°C)
    1 year frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Spec Reject:
    Severely lipemic, hemolyzed, or contaminated sample
  • Methodology:
    Indirect Fluorescent Antibody (IFA)
  • Clinical Significance:
    Refer to:
    ARUP Consult | The Physician's Guide to Laboratory Test Selection and Interpretation
  • Reference Range:
    St. Louis Encephalitis Antibody, IgG by IFA, Serum
    Less than 1:16
    Interpretive Data:
    A positive result for IgG may suggest current or past infection. Antibody to any of the Flavivirus group (Group B viruses) will react quite strongly with the St. Louis encephalitis viral antigen and, therefore, cannot be differentiated further. The specific virus responsible for such a titer must be deduced by the travel history of the patient, along with available medical and epidemiological data, unless the virus can be isolated.
    Note:
    Serum specimens drawn within the first two weeks after onset are variably negative for IgG antibody and should not be used to exclude the diagnosis of arboviral disease. Seroconversion between acute and convalescent sera is considered strong evidence of recent infection. The best evidence for infection is a significant change (fourfold difference in titer) on two appropriately timed specimens, where both tests are performed in the same laboratory at the same time.
  • Day Run:
    Tue, Fri
  • Time Reported:
    2-6 days
  • Test Type:
    INFECTIOUS ANTIBODY