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Test Name:
California Encephalitis IgG Antibody, by IFA, Serum


  • SBMF No:
    44056
  • Performance Lab Name:
    ARUP Laboratories
  • Test Mnemonic:
    CALIF
  • ABN:
    Not required
  • CPT Code:
    86651
  • LOINC Code:
    10904-1
  • Ref Lab Test No:
    0050508
  • Also Known As:
    Encephalitis Antibody, Calfornia, IgG
    CE IgG Ab
    La Crosse Encephalitis IgG Antibody
  • Also See:
    44059 Eastern Equine Encephalitis IgG Antibody, Serum
    44060 St. Louis Encephalitis IgG Antibody, Serum
    28237 West Nile Virus IgG Antibody, Serum
    44061 Western Equine Encephalitis IgG Antibody, Serum
  • Spec Type:
    Serum
  • Spec Container:
    Gold top (SST) or red top (serum) tube
  • Pref Vol:
    1.0 mL
  • Min Vol:
    0.5 mL
    Pediatric Collection: 0.15 mL
  • Fasting:
    No
  • Spec Collect:
    Routine venipuncture
    Parallel testing is preferred
    Label samples as: "acute" or "convalescent"
    Convalescent samples must be received within 30 days from receipt of acute samples
  • Spec Process:
    Clot 30 minutes
    Promptly centrifuge 15 minutes
    Immediately transfer serum to separate plastic tube
  • Spec Store Transport:
    Refrigerated
  • Spec Stability:
    After separation from cells:
    48 hours room temperature (20-30°C)
    2 weeks refrigerated (2-8°C)
    1 year frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Spec Reject:
    Severely lipemic, contaminated, or hemolyzed sample
  • Methodology:
    Indirect Fluorescent Antibody (IFA)
  • Clinical Significance:
    Refer to:
    ARUP Consult | The Physician's Guide to Laboratory Test Selection and Interpretation
  • Reference Range:
    California Encephalitis Antibody, IgG by IFA, Serum
    Less than 1:16
    Interpretive Data:
    A positive result for IgG may suggest current or past infection. La Crosse virus is related to viruses within the California Encephalitis Group and, generally, is reactive with antibody to other viruses within this group.
    Note:
    Serum specimens drawn within the first two weeks after onset are variably negative for IgG antibody and should not be used to exclude the diagnosis of arboviral disease. Seroconversion between acute and convalescent sera is considered strong evidence of recent infection. The best evidence for infection is a significant change (fourfold difference in titer) on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.
  • Day Run:
    Tue, Fri
  • Time Reported:
    2-6 days
  • Test Type:
    INFECTIOUS ANTIBODY