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Test Name:
Soluble Transferrin Receptor

• SBMF No:
  44004
• Performance Lab Name:
  ARUP Laboratories
• Test Mnemonic:
  STR
• ABN:
  Not required
• CPT Code:
  84238
• LOINC Code:
  33210-6
• Ref Lab Test No:
  0070283
• Also Known As:
  sTfR
  Transferrin Receptor Level
• Also See:
  29100 Iron and Iron Binding Capacity, Serum
  30055 Ferritin
• Spec Type:
  Serum
• Spec Container:
  Gold top (SST) or red top (serum) tube
• Alt Spec Type:
  Plasma
• Alt Spec Container:
  Green top (heparin) tube
• Pref Vol:
  1.0 mL
• Min Vol:
  0.3 mL
• Fasting:
  No
• Spec Collect:
  Routine venipuncture
• Spec Process:
  Serum sample tubes, clot 30 minutes
  Promptly centrifuge 15 minutes
  Immediately transfer serum or plasma to separate plastic tube
• Spec Store Transport:
  Refrigerated
• Spec Stability:
  After separation from cells:
  3 days room temperature (20-30°C)
  1 week refrigerated (2-8°C)
  1 month frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  1 year deep-frozen (-70°C)
• Spec Reject:
  Severely hemolyzed, icteric, contaminated or lipemic sample
• Methodology:
  Immunoturbidimetric Assay
• Clinical Significance:
  Refer to:
  
• Reference Range:
  

  Male - 18 years & older: 2.2-5.0 mg/L
  Female - 18 years & older: 1.9-4.4 mg/L

  Interpretive Data:
  People of African descent and those residing at 5,200 feet (1,600 meters) above sea level were found to have a 6% higher normal value. These differences were additive. Reference intervals have not been established for pregnant females, patients under 18 years of age, and recent or frequent blood donors.

  Serum soluble transferrin receptor increases in iron deficiency and is usually unaffected by chronic disease states. In general, to increase sensitivity and specificity, the measurement of serum soluble transferrin receptor should be performed in combination with other tests of iron status, including ferritin, TIBC, and serum iron (refer to table below).

  	Tests for Changes in:	Iron Deficiency    Anemia	Anemia of Chronic   Disease	Iron Deficiency & Anemia of Chronic Disease
  Ferritin	Iron Stores	Low	High	Normal or High
  TIBC	Iron Status	High	Low	Normal or High
  Serum Iron	Iron Status	Low	Low	Low
  sTfR	Iron Status	High	Normal	High

• Day Run:
  Sun-Sat (daily)
• Time Reported:
  1-2 days
• Test Type:
  CHEMISTRY