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Test Name:
IGF Binding Protein-2


  • SBMF No:
    43210
  • Performance Lab Name:
    Quest Diagnostics Nichols Institute
  • Test Mnemonic:
    IGFBP-2
  • ABN:
    Required – Not FDA-Approved
  • CPT Code:
    83519
  • Ref Lab Test No:
    37102X
  • Also Known As:
    IGFBP-2
  • Spec Type:
    Serum
  • Spec Container:
    Red top (serum) tube
  • Pref Vol:
    1.0 mL
  • Min Vol:
    0.2 mL
  • Fasting:
    No
  • Spec Process:
    Clot 30 minutes
    Promptly centrifuge 15 minutes
    Immediately transfer serum to separate plastic tube and freeze
  • Spec Store Transport:
    Frozen
  • Spec Stability:
    After separation from cells:
    8 hours room temperature (20-30°C)
    48 hours refrigerated (2-8°C)
    1 year frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Spec Reject:
    Non-frozen sample
  • Methodology:
    Radioimmunoassay (RIA)
  • Clinical Significance:
    The concentration of IGFBP-2 is inversely correlated with changes in growth hormone (hGH) secretion. IGFBP-2 may also be used as a marker of metastatic prostatic carcinoma.
  • Reference Range:
    1- 9 Years: 69-480 ng/mL
    10-17 Years: 50-326 ng/mL
    18-49 Years: 55-240 ng/mL
    >49 Years: 28-444 ng/mL
  • Additional Test Info:
    This test was developed and its performance characteristics have been determined by Quest Diagnostics Nichols Institute, San Juan Capistrano. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. Performance characteristics refer to the analytical performance of the test.
  • Day Run:
    Sets up 1 day a week
  • Time Reported:
    Reports in 2 days
  • Test Type:
    HORMONE