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Test Name:
Estrogens, Total

• SBMF No:
  43116
• Performance Lab Name:
  Quest Diagnostics Nichols Institute
• Test Mnemonic:
  SLI ESTRO
• ABN:
  Not required
• CPT Code:
  82672
• LOINC Code:
  19146-0
• Ref Lab Test No:
  3164
• Also See:
  30127 Estrogens, Fractionated
• Spec Type:
  Serum
• Spec Container:
  Gold top (SST) or red top (serum) tube
• Alt Spec Type:
  Plasma
• Alt Spec Container:
  Green top (heparin) tube
• Pref Vol:
  3.0 mL
• Min Vol:
  1.5 mL
• Fasting:
  No
• Spec Collect:
  Routine venipuncture
• Spec Process:
  Serum sample tubes, clot 30 minutes
  Promptly centrifuge 15 minutes
  Immediately transfer serum or plasma to separate plastic tube
• Spec Store Transport:
  Refrigerated
• Spec Stability:
  48 hours room temperature (20-30°C)
  7 days refrigerated (2-8°C)
  2 months frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
• Methodology:
  Radioimmunoassay (RIA)
• Use:
  Evaluate for ovarian estrogen producing tumor in the premenarcheal and postmenopausal female; evaluate estrogen excess in males. Estrogen analysis may be helpful in establishing time of ovulation and optimal time for conception. Serial samples must be collected over several days to evaluate baseline and peak total estrogen levels.
  NOTE: Estrogen results obtained using separate specific assays for estrone and estradiol better reflect in vivo estrogen production than results obtained using the non-specific RIA method for total estrogens. Refer to Estrogens, Fractionated (30127).
• Reference Range:
  REFERENCE RANGE for Total Estrogens (E1 plus E2):

  	Female cycle    1-10 days    11-20 days    21-30 days Prepubertal Postmenopausal Adult Male		61-394 pg/mL 122-437 pg/mL 156-350 pg/mL Less than 40 pg/mL Less than 40 pg/mL Less than 200 pg/mL
  	hMG treatment (therapeutic range): 400-800 pg/mL

  For specific assessment of estrogen levels, request Estrone and Estradiol.

• Day Run:
  Sun, Tue-Sat
• Time Reported:
  Same day
  This is a sendout test. Please note that turnaround time is defined as the anticipated time from set up day to results release.
• Test Type:
  HORMONE