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Test Name:
Allergen, Food of Animal Origin, Cow's Milk IgG


  • SBMF No:
    43030
  • Performance Lab Name:
    Quest Diagnostics Nichols Institute
  • Test Mnemonic:
    F2G
  • ABN:
    Required – Allergen specific IgG testing (CPT code 86001) is considered to be not medically necessary and will be denied
  • CPT Code:
    86001
  • LOINC Code:
    19146-0
  • Ref Lab Test No:
    F2G
  • Also Known As:
    Cow's milk Specific IgG, ImmunoCAP™ f2
    Bos spp.
  • Also See:
    28585 Allergen, Food of Animal Origin, Casein IgE
    28481 Allergen, Food of Animal Origin, Cow's Milk IgE
  • Spec Type:
    Serum
  • Spec Container:
    Gold top (SST) or red top (serum) tube
  • Pref Vol:
    1.0 mL
  • Min Vol:
    0.3 mL
  • Fasting:
    No
  • Spec Collect:
    Routine venipuncture
  • Spec Process:
    Clot 30 minutes
    Promptly centrifuge 15 minutes
    Immediately transfer serum to separate plastic tube
  • Spec Store Transport:
    Room temperature or refrigerated
  • Spec Stability:
    7 days room temperature (20-30°C)
    14 days refrigerated (2-8°C)
    30 days frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Methodology:
    ImmunoCAP™ Fluorescent Enzyme Immunoassay (FEIA)
  • Use:
    Detection of allergen-specific IgG antibody
  • Clinical Significance:
    Although there have been many publications concerning the measurement of allergen-specific IgG, the clinical utility of such tests has not been established except in special situations. Thus, the quantitative IgG test should only be ordered by specialists who recognize the limitations of the test. The normal reference ranges reported represent the expected results for individuals who have no unusual exposure and have not been immunized with the indicated allergen. The ranges reported have no disease-associated significance.
  • Reference Range:
    < 2.0 mcg/mL
  • Additional Test Info:

    The occurrence of IgG antibodies to cow's milk is a physiologic phenomenon without diagnostic significance. Testing IgE Casein (ImmunoCAP™ f78) is recommended if cow's milk allergy is suspected as casein is the major allergenic and antigenic protein in cow's milk. (Keller KM, et al., Klin Paediatr 1999;211:384-8.)

    This test is performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics Nichols Institute, Valencia. This test should not be used for diagnosis without confirmation by other medically established means.

  • Day Run:
    Sun, Wed, Fri
  • Time Reported:
    Same day
    This is a sendout test. Please note that turnaround time is defined as the anticipated time from set up day to results release.
  • Test Type:
    ALLERGENS