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Test Name:
Pigeon Breeders Disease Serology


  • SBMF No:
    42088
  • Performance Lab Name:
    Mayo Medical Laboratories
  • Test Mnemonic:
    PIGEON SER
  • ABN:
    Not required
  • CPT Code:
    86671
  • Ref Lab Test No:
    8892
  • Also Known As:
    Avian Protein
  • Spec Type:
    Serum
  • Spec Container:
    Red top (serum) or gold top (SST) tube
  • Pref Vol:
    0.2 mL
  • Min Vol:
    0.1 mL
  • Fasting:
    No
  • Spec Collect:
    Routine venipuncture
  • Spec Process:
    Clot 30 minutes
    Promptly centrifuge 15 minutes
    Immediately transfer serum to separate plastic tube
  • Spec Store Transport:
    Refrigerated
  • Spec Reject:
    Specimens other than serum
    Room temperature sample
  • Methodology:
    Fluorescence Enzyme Immunoassay (FEIA)
  • Use:
    Evaluation of patients suspected of having hypersensitivity pneumonitis induced by exposure to pigeon droppings
  • Clinical Significance:
    Avian proteins, including antigens in pigeon droppings, are a causative agent of hypersensitivity pneumonitis (HP). While the immunopathogenesis of HP is not known, several immune mechanisms are postulated to play a role, including both cellular and humoral mechanisms.
  • Reference Range:

    > or = 16 years: < or = 53.3 mg/L

    Interpretive Data:
    Elevated concentrations of IgG antibodies to pigeon droppings are consistent with the diagnosis of hypersensitivity pneumonitis caused by exposure to this antigen.

    Negative results do not rule out the disease.

    Elevated concentrations of IgG antibodies to pigeon droppings were found in a small number of sera from patients with hypersensitivity pneumonitis (10%).

    Cautions:
    IgG antibodies to pigeon droppings are detectable in healthy individuals, and the presence of antibodies is not sufficient to establish the diagnosis of hypersensitivity pneumonitis (HP) caused by exposure to this antigen.

    The levels of antibodies decrease following successful treatment of HP; but, elevated levels may persist for long periods.

    The measurement of IgG antibodies to pigeon droppings should not be relied upon exclusively to establish the diagnosis of HP.

  • Additional Test Info:

    This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions.

    Reference:
    "Pigeon Breeders Disease Serology, Serum." 2011 Online Test Catalog, Mayo Medical Laboratories, 2011. Web. 30 July 2011 <http://www.mayomedicallaboratories.com/test-catalog/Overview/8892>

  • Day Run:
    Mon-Sat
  • Time Run:
    Mon-Fri: 9:00 am
    Sat: 8:00 am
  • Time Reported:
    2-4 days
  • Test Type:
    IMMUNOLOGY