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Test Name:
Fibrillarin U3 RNP
- SBMF No:
33063 - Performance Lab Name:
Rheumatology Diagnostics Laboratory - Test Mnemonic:
U3 RNP - ABN:
Required – Not FDA-Approved - CPT Code:
86235 - LOINC Code:
19146-0 - Ref Lab Test No:
232 (Quest# S50695) - Also Known As:
U3-RNP
U3RNP - Spec Type:
Serum - Spec Container:
Gold top (SST) or red top (serum) tube - Pref Vol:
1.0 mL - Min Vol:
0.5 mL - Fasting:
No - Spec Collect:
Routine venipuncture - Spec Process:
Clot 30 minutes
Promptly centrifuge 15 minutes
Immediately transfer serum to separate plastic tube - Spec Store Transport:
Refrigerated - Spec Stability:
3 days room temperature (20-30°C)
2 weeks refrigerated (2-8°C)
6 months frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles - Methodology:
Immunoprecipitation - Use:
The U3-RNP (Fibrillarin) particle is thought to participate in the first step of pre-ribosomal RNA processing. Anti-U3-RNP Abs have been shown to be highly specific for patients with SSC. - Reference Range:
Negative - Additional Test Info:
This test was developed and its performance characteristics validated by RDL Inc. The FDA has determined that approval for this test is not necessary. This is an analyte specific reagent (ASR) test.
This test is referred through Quest Diagnostics Nichols Institute.
- Day Run:
Wed - Time Reported:
Within 2 weeks - Test Type:
IMMUNOLOGY
