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Test Name:
Brucella IgG and IgM Antibodies, by ELISA


  • SBMF No:
    33060
  • Performance Lab Name:
    Focus Diagnostics
  • Test Mnemonic:
    BRUC GM
  • ABN:
    Not required
  • CPT Code:
    86622x2
  • LOINC Code:
    19146-0
  • Ref Lab Test No:
    40010 (Quest# S51666)
  • Test Includes:
    Brucella IgG Antibody, by ELISA
    Brucella IgM Antibody, by ELISA
  • Also See:
    44605 Brucella Total Antibody, by Agglutination
  • Spec Type:
    Serum
  • Spec Container:
    Gold top (SST) or red top (serum) tube
  • Pref Vol:
    1.0 mL
  • Min Vol:
    0.2 mL
  • Fasting:
    No
  • Spec Collect:
    Routine venipuncture
  • Spec Process:
    Clot 30 minutes
    Promptly centrifuge 15 minutes
    Immediately transfer serum to separate plastic tube
  • Spec Store Transport:
    Refrigerated
  • Spec Stability:
    7 days room temperature (20-30°C)
    14 days refrigerated (2-8°C)
    30 days frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Methodology:
    Enzyme-Linked Immunosorbent Assay (ELISA)
  • Clinical Significance:
    Acute brucellosis is characterized by the appearance of Brucella-specific IgM within the first week of infection, followed by the appearance of Brucella-specific IgG after the second week. Levels of both IgM and IgG decline slowly over several months in conjunction with recovery. Persistence of high IgG levels with declining or absent IgM suggests chronic infection or relapse.
  • Reference Range:
    < 0.80 U
  • Additional Test Info:
    This test is referred through Quest Diagnostics Nichols Institute.
  • Day Run:
    Mon, Wed, Fri
  • Time Reported:
    3-5 days
  • Test Type:
    INFECTIOUS ANTIBODY

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