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Test Name:
Gamma-Hydroxybutyric Acid, Urine
- SBMF No:
31181 - Performance Lab Name:
Toxicology - Test Mnemonic:
GHB GC/MS - ABN:
Not required - CPT Code:
82542 - LOINC Code:
57746-0 - Also Known As:
GHB - Spec Type:
Urine, random - Spec Container:
Plastic container with tightly fitting lid (No preservative) - Pref Vol:
10.0 mL - Min Vol:
5.0 mL - Spec Collect:
Random urine sample should be collected as soon as possible after symptoms of exposure to drug
– Note: Drug may be detectable only a few hours post-ingestion - Spec Process:
Keep container tightly sealed
Refrigerate promptly after collection - Spec Store Transport:
Refrigerated - Spec Stability:
1 week refrigerated (2-8°C) - Spec Reject:
Specimens other than urine - Spec Remarks:
More than 95% of an oral dose of GHB is metabolized to carbon dioxide and water, leaving less than 5% to be detected in excreted urine, and it is undetectable after twelve hours. - Methodology:
Gas Chromatography/Mass Spectrometry (GC/MS) - Use:
Detect presence of Gamma-Hydroxybutyrate (GHB) - Clinical Significance:
Gamma-Hydroxybutyrate (GHB) is a naturally occurring substance present in the tissues of humans and other mammals. GHB may be synthesized as a sodium salt and used as a rapid acting anesthetic and hypnotic agent. Currently, legitimate use of synthesized GHB in the United States is limited to investigational purposes only. However, GHB has been marketed illicitly since the 1990s. GHB has been used by athletes to increase muscle mass and more recently as a club drug in "rave" clubs along with other club drugs such as LSD, MDMA and Rohypnol®. The effects of GHB when taken orally are dose dependent and range from dizziness, euphoria, and mild sedation to levels of deep sleep. - Reference Range:
Negative (less than 10 µg/mL) - Day Run:
Tue, Thu - Time Run:
7:30 am - Time Reported:
1-4 days - Test Type:
TOX-TDM
