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Test Name:
Flunitrazepam Metabolite, by GC/MS, Urine
- SBMF No:
31180 - Performance Lab Name:
Toxicology - Test Mnemonic:
FLU GC/MS - ABN:
Not required - CPT Code:
82542 - LOINC Code:
19467-0; 31208-2 - Test Includes:
7-Aminoflunitrazepam (primary metabolite of flunitrazepam) - Also Known As:
Rohypnol®
Roofies - Spec Type:
Urine, random - Spec Container:
Plastic container with tightly fitting lid (No preservative) - Pref Vol:
10.0 mL - Min Vol:
5.0 mL - Spec Collect:
Random urine sample should be collected as soon as possible after symptoms of exposure to drug
– Note: Drug may not be detectable after 12-24 hours post-ingestion - Spec Process:
Keep container tightly sealed
Refrigerate promptly after collection - Spec Store Transport:
Refrigerated - Spec Stability:
1 week refrigerated (2-8°C) - Spec Reject:
Specimens other than urine - Methodology:
Quantitative Gas Chromatography/Mass Spectrometry (GC/MS) - Use:
Detect presence of Flunitrazepam metabolite - Clinical Significance:
Flunitrazepam (Rohypnol®) is a hypnotic and anesthetic induction agent available in several western European countries. Despite its clinical use throughout the world, Flunitrazepam has never been approved by the Food and Drug Administration for use in the United States. Recently, Flunitrazepam has become a problem in the United States due to illicit trafficking and an increase in recreational use. Most notably, the misuse of Flunitrazepam has been implicated with date rape in a number of U.S. cities. The detection of Flunitrazepam in urine is rare given its rapid and extensive biotransformation to the major urinary metabolite 7-aminoflunitrazepam and at least 10 other metabolites. To effectively detect the presence of this drug, this procedure specifically targets the Flunitrazepam metabolite, 7-aminoflunitrazepam. - Reference Range:
Negative (less than assay limit of detection) - Day Run:
Tue, Thu - Time Run:
7:30 am - Time Reported:
1-4 days - Test Type:
TOX-TDM
