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Test Name:
Drug Screen 4, with Confirmation/Quantitation if Indicated, Meconium
- SBMF No:
31170 - Performance Lab Name:
Toxicology - Test Mnemonic:
MEC 4 - ABN:
May be required – Medical Necessity - CPT Code:
80101x4
If positive, add appropriate CPT for drug confirmed: 82145 Amphetamines; 82520 Cocaine; 83925 Opiates; 82542 Marijuana
Medicare: G0431
If positive, add appropriate CPT for drug confirmed: 82145 Amphetamines; 82520 Cocaine; 83925 Opiates; 82542 Marijuana - LOINC Code:
48767-8; 8146-3; 8189-3; 8216-4; 31080-5; 48767-8 - Test Includes:
Amphetamines
Cocaine
Opiates
Marijuana (THC Metabolite) - Also Known As:
Meconium Drug Screen - Spec Type:
Meconium (infant’s initial stool sample) - Spec Container:
Plastic container with tightly fitting lid - Pref Vol:
All meconium available (5 grams preferred) - Min Vol:
1 gram - Spec Collect:
Collect all meconium (dark green or greenish black material) in plastic container with tightly fitting lid
Note: Yellow or yellowish-green material indicates that the specimen is predominantly feces and is not suitable for testing - Spec Process:
Refrigerate promptly after collection - Spec Store Transport:
Refrigerated - Spec Stability:
1 week refrigerated (2-8°C)
1 month frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles - Spec Reject:
Sample other than meconium - Methodology:
Qualitative Enzyme-Linked Immunosorbent Assay (ELISA) [High Complexity] - Use:
Indicator of in utero drug exposure - Clinical Significance:
Meconium is the intestinal contents of a newborn infant that is excreted as the first stool. It is a dark green, semisolid material derived from biological waste such as intestinal secretions, fatty material, amniotic fluid, lanugo and various tissue cells. Meconium starts forming at approximately 16 weeks of gestation and accumulates during the rest of the gestational period. Drugs that a fetus is exposed to in utero are excreted into the fetal bile, which accumulates directly in the meconium. Thus, meconium testing may be used to derive information regarding gestational drug exposure. - Reference Range:
MECONIUM 4 DRUG SCREEN Amphetamines NEGATIVE Cocaine NEGATIVE Opiates NEGATIVE THC Metabolite NEGATIVE TEST INFORMATION: Meconium Drug Screen MEC 4
1. Cutoff concentrations, ng/g:
Amphetamines
Cocaine
Opiates
THC MetaboliteInitial Test
200
150
200
40Confirmation
20
20
2
52. Initial tests by enzyme immunoassay 3. Drugs covered Amphetamines: amphetamine, methamphetamine, methylene-
dioxymethamphetamine (MDMA-Ecstasy), and methylene-
dioxyamphetamine (MDA).
Cocaine, benzoylecgonine, m-hydroxybenzoylecgonine,
cocaethylene
Opiates: codeine, dihydrocodeine, morphine, 6-acetyl-
morphine, hydrocodone, hydromorphone, oxycodone,
oxymorphone
THC MetaboliteINITIAL TESTS PERFORMED AT:
SBMF - Central Lab, South Bend, IN 46601 CLIA #15D0357169CONFIRMATION TEST(S), IF INDICATED, PERFORMED AT:
ARUP Laboratories, Salt Lake City, Utah CLIA #46D0523979 - Additional Test Info:
Screen-positive specimens are automatically confirmed by GC/MS or LC-MS/MS. Additional charges may apply. - Day Run:
Tue, Thu - Test Type:
TOX-TDM