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Test Name:
Ethyl Glucuronide Screen, by EIA, with Confirmation/Quantitation if Indicated, Urine


  • SBMF No:
    31167
  • Performance Lab Name:
    Toxicology
  • Test Mnemonic:
    ETG/C
  • ABN:
    May be required – Medical Necessity
  • CPT Code:
    80101
    If indicated, add 82542
    Medicare: G0434
    If indicated, add 82542
  • LOINC Code:
    58400-3; 58375-7; 2161-8
  • Test Includes:
    Screening test with Confirmation if indicated
  • Also Known As:
    EtG Screen with Confirmation
  • Spec Type:
    Urine, random
  • Spec Container:
    Plastic container with tightly fitting lid (No preservative)
  • Pref Vol:
    10.0 mL
  • Min Vol:
    5.0 mL
  • Spec Collect:
    Routine random urine collection
  • Spec Process:
    Keep container tightly sealed
    Refrigerate promptly after collection
  • Spec Store Transport:
    Refrigerated
  • Spec Stability:
    1 week refrigerated (2-8°C)
    1 month frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Spec Reject:
    Specimens other than urine
  • Methodology:
    Enzyme Immunoassay (EIA) [Moderate Complexity]
    Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
  • Use:
    Biological marker for monitoring ethanol (alcohol) ingestion
  • Clinical Significance:
    Ethyl Glucuronide (EtG) is a non-volatile metabolite of ethanol formed via enzymatic conjugation of ethanol and glucuronic acid. EtG is a stable compound that can be detected in urine samples 72–96 hours after ethanol ingestion, which is considerably longer than the 12–14 hour detection period of its parent compound, ethanol. Given its long detection time, EtG can be a useful diagnostic parameter for monitoring alcohol abstinence. EtG is produced only after hepatic exposure and not as a result of fermentation; thus, the potential problem of false positive alcohol results in samples from diabetic individuals is eliminated. To ensure that positive EtG results are not a consequence of incidental exposure (e.g., over the counter products containing alcohol, hand sanitizers, cosmetics, etc.) the South Bend Medical Foundation has elected to use a positive cut-off of 250 ng/mL.
  • Reference Range:
    Less than 250 ng/mL
  • Day Run:
    EIA Screening: Mon-Fri
    LC-MS/MS Confirmation: Tue, Thu
  • Test Type:
    TOX-TDM

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