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Test Name:
Drug Screen with Volatiles, Blood

• SBMF No:
  31163
• Performance Lab Name:
  Toxicology
• Test Mnemonic:
  SDSVO-
• ABN:
  May be required – Medical Necessity
• CPT Code:
  80100; 80101x5; 84600

  ---

  Medicare: G0431; G0434; 84600
• LOINC Code:
  15401-3; 39111-0
• Test Includes:
  acetaminophen, alprazolam, amitriptyline, amphetamine, amobarbital, benzodiazepine class, brompheniramine, bupropion, butabarbital, butalbital, carbamazepine, carisoprodol, chlordiazepoxide, chlorpheniramine, clomipramine, clonazepam, clorazepate (as nordiazepam), cocaine metabolite, codeine, cyclobenzaprine, desalkylflurazepam, dextromethorphan, diazepam, dihydrocodeine, diphenydramine, doxepin, doxylamine, ephedrine/pseudoephedrine, ethosuximide, flurazepam, fluoxetine, glutehimide, hydrocodone, hydromorphone, hydroxyzine, ibuprofen, imipramine, lidocaine, lorazepam, MDA, MDMA, meperidine, meprobamate, methadone, methamphetamine, methaqualone, metoprolol, morphine, NAPA, naproxen, nordiazepam, nortriptyline, opiate class, oxycodone, pentazocine, pentobarbital, phencyclidine, phenobarbital, phentermine, phenylpropanolamine, phenytoin, primidone, procainamide, promethazine, propoxyphene, pseudophedrine/ephedrine, salicylate, secobarbital, sertraline, temazepam, THC (marijuana metabolite), theophylline, thioridazine, tramadol, trazodone, trimipramine, tripelennamine, venlafaxine, verapamil, volatiles (acetone, ethanol, isopropanol, methanol)
• Also See:
  31162 Drug Screen without Volatiles, Blood
  31035 Volatiles, Blood
• Spec Type:
  Serum
• Spec Container:
  Red top (serum) tube
• Alt Spec Type:
  Whole blood
• Alt Spec Container:
  Gray top (fluoride/oxalate) tube
• Pref Vol:
  3.0 mL
• Min Vol:
  1.0 mL
• Fasting:
  No
• Spec Collect:
  Do not use gel-barrier tubes for specimen collection
  Prep venipuncture site with non-alcohol containing prepping agent
  Routine venipuncture
  Fill collection tube to vacuum capacity to minimize evaporation of volatiles
  Note anatomical draw site on specimen label and test request form
• Spec Process:
  Do not centrifuge
  Do not remove tube stopper (tube must remain tightly stoppered)
  Do not remove serum or plasma from cells
• Spec Store Transport:
  Refrigerated
• Spec Stability:
  1 week refrigerated (2-8°C)
• Methodology:
  Enzyme Immunoassay (EIA) [Moderate Complexity]
  Gas Chromatography (GC) [High Complexity]
  Gas Chromatography/Mass Spectrometry (GC/MS) [High Complexity]
  Color Spot Tests [Moderate Complexity]
• Use:
  Detect drug use
  Evaluate toxicity
• Clinical Significance:
  Drugs or drug metabolites may be detected by a variety of techniques. This procedure utilizes the techniques of Gas Chromatography/Mass Spectrometry (GC/MS), Gas Chromatography (GC), Enzyme Immunoassay (EIA), and color spot tests. The lower limit of detection for most drugs detectable by the procedure ranges from 0.5 to 2.0 mcg/mL. The EIA test is generally more sensitive and may have lower limits of detection. EIA results may be reported as being positive for a drug class, since the EIA technique does not necessarily identify a specific drug (e.g., Opiates). This procedure can detect most drugs of abuse, many prescription drugs, and many over-the-counter medications. Not all drugs are detectable by this procedure. In particular, it should be noted that LSD, insulin, vitamins, and most antibiotics are not detectable by this procedure. This drug test does not utilize forensic procedures. It is intended for medical purposes.
• Reference Range:
  

  DRUG SCREEN SERUM:
  S Drug Sc Vol
  	Specimen: SERUM  In addition to drug screening by GC/MS, volatiles, color  tests (CT) and immunoassay (IA) tests are routinely  performed.
  	VOLATILES    Ethanol Acetone Isopropanol Methanol	CONCENTRATION    None Detected None Detected None Detected None Detected	GC CUTOFF    5 mg/dL 5 mg/dL 5 mg/dL 5 mg/dL	POTENTIAL 250 mg/dL 30 mg/dL 40 mg/dL 10 mg/dL	TOXICITY

  	Immunoassay and color testing produced the following  results:
  	DRUG Benzodiazepine class Cocaine metabolite Opiate class Oxycodone THC (marijuana metabolite)          Salicylate Acetaminophen	RESULT Negative Negative Negative Negative Negative     Negative Negative	IA CUTOFF 100 ng/mL 100 ng/mL 100 ng/mL 100 ng/mL 10 ng/mL   CT CUTOFF 50 mcg/mL 10 mcg/mL
  	Immunoassay and color test results are not routinely confirmed.

  GC/MS screening produced the following results:
                                    No drugs detected

  List of drugs screened for by GC/MS:
  acetaminophen, alprazolam, amitriptyline, amphetamine, amobarbital, brompheniramine, bupropion, butabarbital, butalbital, carbamazepine, carisoprodol, chlordiazepoxide, chlorpheniramine, clomipramine, clonazepam, clorazepate (as nordiazepam), cocaine, codeine, cyclobenzaprine, desalkylflurazepam, dextromethorphan, diazepam, dihydrocodeine, diphenydramine, doxepin, doxylamine, ephedrine/pseudoephedrine, ethosuximide, flurazepam, fluoxetine, glutehimide, hydrocodone, hydromorphone, hydroxyzine, ibuprofen, imipramine, lidocaine, lorazepam, MDA, MDMA, meperidine, meprobamate, methadone, methamphetamine, methaqualone, metoprolol, morphine, NAPA, naproxen, nordiazepam, nortriptyline, oxycodone, pentazocine, pentobarbital, phencyclidine, phenobarbital, phentermine, phenylpropanolamine, phenytoin, primidone, procainamide, promethazine, propoxyphene, pseudophedrine/ephedrine, secobarbital, sertraline, temazepam, theophylline, thioridazine, tramadol, trazodone, trimipramine, tripelennamine, venlafaxine, verapamil.

  Limit of detection for most drugs = 1 mcg/mL.
  Other drugs not listed may be detected and reported.

  To discuss detectability of specific drugs by these procedures or to inquire about the availability of additional quantitative testing for specific drugs, please call the Toxicology laboratory.

• Day Run:
  Mon-Fri
• Time Run:
  2:00 pm
• Time Reported:
  2-5 days
• Test Type:
  TOX-TDM