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Test Name:
Drug Screen, Comprehensive, Urine

• SBMF No:
  31161
• Performance Lab Name:
  Toxicology
• Test Mnemonic:
  U DS-COMP-
• ABN:
  May be required – Medical Necessity
• CPT Code:
  80100; 80101x15

  ---

  Medicare: G0431; G0434
• LOINC Code:
  41270-0
• Test Includes:
  acetaminophen, acetylmorphine, alprazolam, amitriptyline, amphetamine class, amobarbital, barbiturates, benzodiazepine class, brompheniramine, bupropion, butabarbital, butalbital, carbamazepine, carisoprodol, chlordiazepoxide, chlorpheniramine, clomipramine, clonazepam, clorazepate (as nordiazepam), cocaine metabolite, codeine, cyclobenzaprine, desalkylflurazepam, dextromethorphan, diazepam, dihydrocodeine, diltiazem, diphenydramine, doxepin, doxylamine, ephedrine/pseudoephedrine, ethanol, ethchlorvynol, ethosuximide, flurazepam, fluoxetine, glutehimide, guaifensin, hydrocodone, hydromorphone, hydroxyzine, ibuprofen, imipramine, lidocaine, lorazepam, MDA, MDMA, meperidine, meprobamate, methadone, methamphetamine, methaqualone, metoprolol, morphine, NAPA, naproxen, nordiazepam, nortriptyline, opiate class, oxycodone, pentazocine, pentobarbital, phencyclidine, phenobarbital, phentermine, phenylpropanolamine, phenytoin, primidone, procainamide, promethazine, propoxyphene, pseudophedrine/ephedrine, salicylate, secobarbital, sertraline, temazepam, THC (marijuana metabolite), theophylline, propranolol, thioridazine, tramadol, trazodone, trimipramine, tripelennamine, venlafaxine, verapamil
• Also Known As:
  Comprehensive Urine Drug Screen
• Spec Type:
  Urine, random
• Spec Container:
  Plastic container with tightly fitting lid (No preservative)
• Pref Vol:
  20.0 mL
• Min Vol:
  10.0 mL
• Spec Collect:
  Routine random urine collection
• Spec Process:
  Keep container tightly sealed
  Refrigerate promptly after collection
• Spec Store Transport:
  Refrigerated
• Spec Stability:
  1 week refrigerated (2-8°C)
• Spec Reject:
  Specimens other than urine
• Methodology:
  Enzyme Immunoassay (EIA) [Moderate Complexity]
  Gas Chromatography (GC) [High Complexity]
  Gas Chromatography/Mass Spectrometry (GC/MS) [High Complexity]
  Color Spot Tests [Moderate Complexity]
• Use:
  Detect drug use
• Clinical Significance:
  Exposure to drugs via ingestion or by other route of administration is often detectable by analysis of the urine. Urine is the single best specimen for analysis since the largest number of drugs and drug metabolites are found in this medium. Drugs or drug metabolites may be detected by a variety of techniques. This procedure utilizes the techniques of Gas Chromatography/Mass Spectrometry (GC/MS), Gas Chromatography (GC), Enzyme Immunoassay (EIA), and color spot tests. The lower limit of detection for most drugs detectable by the procedure ranges from 0.5 to 2.0 mcg/mL. The EIA test is generally more sensitive and may have lower limits of detection. EIA results may be reported as being positive for a drug class, since the EIA technique does not necessarily identify a specific drug (e.g., Opiates). This procedure can detect most drugs of abuse, many prescription drugs, and many over-the-counter medications. Not all drugs are detectable by this procedure. In particular, it should be noted that LSD, insulin, vitamins, and most antibiotics are not detectable by this procedure. This drug test does not utilize forensic procedures. It is intended for medical purposes.
• Reference Range:
  

  DRUG SCREEN URINE:
  Urine Drug Scrn
  	Specimen: URINE  In addition to drug screening by GC/MS, color tests (CT),  immunoassay (IA) tests and ethanol analysis are routinely  performed.  Immunoassay, color tests and ethanol analysis produced  the following results:
  	DRUG Amphetamine class Barbiturates Benzodiazepine class Cocaine metabolite Methadone Methaqualone Opiate class Oxycodone PCP Propoxyphene THC (marijuana metabolite)          Salicylate Acetaminophen Ethchlorvynol     Ethanol	RESULT Negative Negative Negative Negative Negative Negative Negative Negative Negative Negative Negative     Negative Negative Negative     Negative	IA CUTOFF 500 ng/mL 200 ng/mL 200 ng/mL 300 ng/mL 300 ng/mL 300 ng/mL 300 ng/mL 300 ng/mL 25 ng/mL 300 ng/mL 20 ng/mL   CT CUTOFF 50 mcg/mL 10 mcg/mL 0.1 mcg/mL        ETHANOL CUTOFF 40 mg/dL
  	Immunoassay and color test results are not routinely confirmed. Ethanol is confirmed by gas chromatography.

  GC/MS screening produced the following results:
                                    No drugs detected

  List of drugs screened for by GC/MS:
  acetaminophen, acetylmorphine, alprazolam, amitriptyline, amphetamine, amobarbital, brompheniramine, bupropion, butabarbital, butalbital, carbamazepine, carisoprodol, chlordiazepoxide, chlorpheniramine, clomipramine, clonazepam, clorazepate (as nordiazepam), cocaine, codeine, cyclobenzaprine, desalkylflurazepam, dextromethorphan, diazepam, dihydrocodeine, diltiazem, diphenydramine, doxepin, doxylamine, ephedrine/pseudoephedrine, ethosuximide, flurazepam, fluoxetine, glutehimide, guaifensin, hydrocodone, hydromorphone, hydroxyzine, ibuprofen, imipramine, lidocaine, lorazepam, MDA, MDMA, meperidine, meprobamate, methadone, methamphetamine, methaqualone, metoprolol, morphine, NAPA, naproxen, nordiazepam, nortriptyline, oxycodone, pentazocine, pentobarbital, phencyclidine, phenobarbital, phentermine, phenylpropanolamine, phenytoin, primidone, procainamide, promethazine, propoxyphene, pseudophedrine/ephedrine, secobarbital, sertraline, temazepam, theophylline, propranolol, thioridazine, tramadol, trazodone, trimipramine, tripelennamine, venlafaxine, verapamil.

  Limit of detection for most drugs = 1 mcg/mL.
  Other drugs not listed may be detected and reported.

  To discuss detectability of specific drugs by these procedures or to inquire about the availability of additional quantitative testing for specific drugs, please call the Toxicology laboratory.

• Day Run:
  Mon-Fri
• Time Run:
  2:00 pm
• Time Reported:
  2-5 days
• Test Type:
  TOX-TDM