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Test Name:
Phencyclidine, by GC/MS, Urine
- SBMF No:
31129 - Performance Lab Name:
Toxicology - Test Mnemonic:
PCP GC/MS - ABN:
Not required - CPT Code:
83992 - LOINC Code:
18392-1; 31208-2 - Also Known As:
PCP
Angel Dust
Sherms - Also See:
29086 Phencyclidine Screen by EIA, Urine - Spec Type:
Urine, random - Spec Container:
Plastic container with tightly fitting lid (No preservative) - Pref Vol:
10.0 mL - Min Vol:
5.0 mL - Spec Collect:
Routine random urine collection - Spec Process:
Keep container tightly sealed
Refrigerate promptly after collection - Spec Store Transport:
Refrigerated - Spec Stability:
1 week refrigerated (2-8°C) - Spec Reject:
Specimens other than urine - Methodology:
Gas Chromatography/Mass Spectrometry (GC/MS) - Use:
Confirm positive screen results
Detect use - Clinical Significance:
Phencyclidine (1-phenylcyclohexylpiperidine) is the most commonly abused member of a class of mind-altering drugs known as dissociatives or arylcyclohexylamines. PCP and its analogs, easily and inexpensively manufactured in clandestine labs, are generally mixed with marijuana or tobacco and smoked. PCP is lipophilic and stored by the body in brain and adipose tissue for considerable periods. The half-life of PCP has been estimated at 7 to 50 hours. Metabolism occurs mainly in the liver through oxidative hydroxylation. PCP is excreted primarily as unchanged drug and inactive conjugates. Complete excretion of the drug usually occurs within 72 hours of administration; however, urine samples may remain positive for as long as two weeks after administration. Renal clearance of PCP is increased markedly with urinary acidification. Plasma and urine concentrations of the drug do not appear to relate to the degree of intoxication. Positive result indicates exposure to drug and does not necessarily indicate impairment. - Reference Range:
Negative (less than assay limit of detection) - Day Run:
Mon-Fri - Time Run:
7:30 am - Time Reported:
2-3 days - Test Type:
TOX-TDM
