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Test Name:
Barbiturates, by GC/MS, Urine


  • SBMF No:
    31121
  • Performance Lab Name:
    Toxicology
  • Test Mnemonic:
    BAR GC/MS
  • ABN:
    Not required
  • CPT Code:
    82205
  • LOINC Code:
    16429-3; 31208-2; 9426-8
  • Test Includes:
    Amobarbital
    Butalbital
    Pentobarbital
    Phenobarbital
    Secobarbital
  • Also Known As:
    Amytal®
    Fiorinal®
    Luminal®
    Nembutal®
    Seconal®
  • Also See:
    29081 Barbiturates Screen by EIA, Urine
  • Spec Type:
    Urine, random
  • Spec Container:
    Plastic container with tightly fitting lid (No preservative)
  • Pref Vol:
    10.0 mL
  • Min Vol:
    5.0 mL
  • Spec Collect:
    Routine random urine collection
  • Spec Process:
    Keep container tightly sealed
    Refrigerate promptly after collection
  • Spec Store Transport:
    Refrigerated
  • Spec Stability:
    1 week refrigerated (2-8°C)
  • Spec Reject:
    Specimens other than urine
  • Methodology:
    Gas Chromatography/Mass Spectrometry (GC/MS)
  • Use:
    Confirm positive screen results by an alternate, specific method; detect use
  • Clinical Significance:
    Barbiturates belong to a broad classification of CNS-depressant drugs known as sedative/hypnotics. Members of the barbiturate family have current medical uses and are prescribed as anticonvulsants, anesthetics, sedatives, and after severe head injury. Barbiturates are lipid soluble and rapidly absorbed into the bloodstream, readily penetrating the blood-brain barrier. Half lives range from 20 to 120 hours. Barbiturates are variously metabolized by the liver, some being excreted in the urine mainly as active and inactive metabolites and others mainly as unchanged drug. Depending on the specific barbiturate taken, urine may test positive for approximately 30 hours after administration or as long as several weeks. Positive result indicates exposure to drug and does not necessarily indicate impairment.
  • Reference Range:
    Negative (less than assay limit of detection)
  • Day Run:
    Mon-Fri
  • Time Run:
    7:30 am
  • Time Reported:
    2-3 days
  • Test Type:
    TOX-TDM