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Test Name:
Phenobarbital, Serum
- SBMF No:
31082 - Performance Lab Name:
Automated Lab - Test Mnemonic:
PHENO - ABN:
Not required - CPT Code:
80184 - LOINC Code:
29637-6; 3948-7 - Also Known As:
Luminal® - Spec Type:
Serum - Spec Container:
Red top (serum) tube - Alt Spec Type:
Plasma - Alt Spec Container:
Green top (lithium heparin) tube - Pref Vol:
0.5 mL - Min Vol:
0.2 mL - Fasting:
No - Spec Collect:
Do not use gel-barrier tubes for specimen collection
Routine venipuncture - Spec Process:
Serum sample tubes, clot 30 minutes
Promptly centrifuge 15 minutes
Immediately transfer serum or plasma to separate plastic tube - Spec Store Transport:
Refrigerated - Spec Stability:
1 week refrigerated (2-8°C) - Spec Remarks:
Uncentrifuged primary sample tube also acceptable - Methodology:
Enzyme Immunoassay (EIA) - Use:
Used in the diagnosis and treatment of phenobarbital overdose and in monitoring levels of the drug to ensure proper therapy - Clinical Significance:
Phenobarbital is used primarily for the long-term treatment of generalized tonic-clonic (grand mal) seizures and cortical focal seizures. For children under five years of age, phenobarbital is the antiepileptic of choice. Older children and adults are treated first with phenytoin; phenobarbital is added if needed. - Reference Range:
0-2 months: 15.0-30.0 μg/mL
> 2 months-Adult: 15.0-40.0 μg/mL - Critical High Value:
60.1 μg/mL - Day Run:
Sun-Sat (daily) - Time Run:
As received - Time Reported:
4 hours - Test Type:
TOX-TDM
