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Test Name:
Dexamethasone Suppression Test, Low Dose, AM Serum Cortisol Level Only


  • SBMF No:
    30204
  • Performance Lab Name:
    Automated Lab
  • Test Mnemonic:
    CORT SUPR
  • ABN:
    Not required
  • CPT Code:
    82533
  • LOINC Code:
    2143-6
  • Also Known As:
    Cortisol Suppression Test
    DST
  • Also See:
    30203 Dexamethasone Suppression Test, AM and PM Serum Cortisol Levels
    30202 Cortisol, Serum
    43209 Dexamethasone, Serum or Plasma
  • Spec Type:
    Serum
  • Spec Container:
    Gold top (SST) or red top (serum) tube
  • Alt Spec Type:
    Plasma
  • Alt Spec Container:
    Lavender top (EDTA) or green top (lithium heparin) tube
  • Pref Vol:
    1.0 mL
  • Min Vol:
    0.2 mL
  • Fasting:
    No
  • Patient Prep:
    1 mg dexamethasone administered between 23:00 and midnight
  • Spec Collect:
    Collect at 08:00
    Routine venipuncture
  • Spec Process:
    Serum sample tubes, clot 30 minutes
    Promptly centrifuge 15 minutes
    Immediately transfer serum or plasma to separate plastic tube
    Properly centrifuged gel barrier tube sample does not require transfer of serum to separate tube
  • Spec Store Transport:
    Refrigerated
  • Spec Stability:
    5 days refrigerated (2-8°C)
    3 months frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Methodology:
    Electrochemiluminescent Immunoassay (ECLIA)
  • Use:
    Evaluation of patient with suspected adrenal hyperfunction (Cushing's Syndrome)
  • Reference Range:
    Dexamethasone Suppression Test, Low Dose
    Cortisol, AM: Less than 6 ug/dL
    Interpretive Data:
    Reference range based on an 08:00 draw following a 1 mg dexamethasone dose administered between 23:00 and midnight.
  • Day Run:
    Sun-Sat (daily)
  • Time Run:
    As received
  • Time Reported:
    4 hours
  • Test Type:
    HORMONE