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Test Name:
Dexamethasone Suppression Test, AM and PM Serum Cortisol Levels


  • SBMF No:
    30203
  • Performance Lab Name:
    Automated Lab
  • Test Mnemonic:
    DEXA SUP
  • ABN:
    Not required
  • CPT Code:
    82533x2
  • LOINC Code:
    29637-6; 19151-0; 19151-0; 9812-9; 9813-7
  • Also Known As:
    Cortisol Suppression Test
    DST
  • Also See:
    30204 Dexamethasone Suppression Test, Low Dose, AM Serum Cortisol Level Only
    30202 Cortisol, Serum
    43209 Dexamethasone, Serum or Plasma
  • Spec Type:
    Serum
  • Spec Container:
    Gold top (SST) or red top (serum) tube
  • Alt Spec Type:
    Plasma
  • Alt Spec Container:
    Lavender top (EDTA) tube or green top (lithium heparin) tube
  • Pref Vol:
    1.0 mL
  • Min Vol:
    0.2 mL
  • Fasting:
    No
  • Patient Prep:
    Dexamethasone administration, dose and time per physician order
  • Spec Collect:
    Collect both a.m. and p.m. samples following administration of dexamethasone
    Specific collection times per physician order
    Routine venipuncture
  • Spec Process:
    Serum sample tubes, clot 30 minutes
    Promptly centrifuge 15 minutes
    Immediately transfer serum or plasma to separate plastic tube
    Properly centrifuged gel barrier tube sample does not require transfer of serum to separate tube
  • Spec Store Transport:
    Refrigerated
  • Spec Stability:
    5 days refrigerated (2-8°C)
    3 months frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Methodology:
    Electrochemiluminescent Immunoassay (ECLIA)
  • Use:
    Evaluation of patient with suspected adrenal hyperfunction (Cushing's Syndrome)
  • Reference Range:
    Cortisol, AM
    6.0 - 25.0 ug/dL
    Cortisol, PM
    4.0 - 14.0 ug/dL
  • Day Run:
    Sun-Sat (daily)
  • Time Run:
    As received
  • Time Reported:
    4 hours
  • Test Type:
    HORMONE