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Test Name:
Toxoplasma IgG and IgM Antibodies


  • SBMF No:
    28137
  • Performance Lab Name:
    Manual Lab
  • Test Mnemonic:
    TOXO AB
  • ABN:
    Not required
  • CPT Code:
    86777; 86778
  • LOINC Code:
    5388-4; 5390-0; 48767-8
  • Test Includes:
    Toxoplasma IgG Antibody
    Toxoplasma IgM Antibody
  • Also Known As:
    Toxoplasma gondii IgG and IgM Antibodies, Serum
  • Also See:
    28139 Toxoplasma IgG Antibody
    28138 Toxoplasma IgM Antibody
  • Spec Type:
    Serum
  • Spec Container:
    Gold top (SST) or red top (serum) tube
  • Pref Vol:
    1.0 mL
  • Min Vol:
    0.5 mL
  • Fasting:
    No
  • Spec Collect:
    Routine venipuncture
  • Spec Process:
    Clot 30 minutes
    Promptly centrifuge 15 minutes
    Immediately transfer serum to separate plastic tube
    Properly centrifuged gel barrier tube sample does not require transfer of serum to separate tube
  • Spec Store Transport:
    Refrigerated (3 days) or frozen
  • Spec Stability:
    3 days (72 hours) refrigerated (2-8°C)
    3 months frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Spec Reject:
    Severely icteric or heat-inactivated sample
  • Methodology:
    Chemiluminescent Immunoassay (ChLIA)
  • Use:
    Support the diagnosis of toxoplasmosis; document past exposure; diagnose acute toxoplasmosis
  • Clinical Significance:
    Toxoplasmosis, caused by the parasite Toxoplasma gondii, has been implicated in serious congenital abnormalities following maternal infections just prior to or during pregnancy. Usually a mild or asymptomatic disease in adults, toxoplasmosis acquired in utero has resulted in blindness, encephalomyelitis, mental retardation, convulsions, and death in infected neonates. In addition, predisposition to severe toxoplasmosis infection is common in persons with acquired immunodeficiency syndrome (AIDS) or in persons who are otherwise immunocompromised.
  • Reference Range:

    Toxoplasma IgG Antibody

         REFERENCE RANGE     INTERPRETATION
    < 6.4 IU/mL     Negative;no infection or exposure is likely.
    6.4-9.9 IU/mL     Indeterminate; repeat testing on a new sample in 10-14 days is recommended.
    >or= 10.0 IU/mL    Positive;indicative of a previous exposure to the organism.

    Toxoplasma IgM Antibody

         REFERENCE RANGE     INTERPRETATION
         < 0.90  Negative
         0.90 - 0.99  Indeterminate
         >= 1.0  Positive

    The CDC recommends that positive T.gondii IgM be confirmed by a different method.

  • Day Run:
    Tue, Sat
  • Time Run:
    8:00 am
  • Time Reported:
    5:00 pm
  • Test Type:
    INFECTIOUS ANTIBODY

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