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Test Name:
IgA, IgG, and IgM Immunoglobulins, Quantitative, Serum


  • SBMF No:
    28130
  • Performance Lab Name:
    Immunology
  • Test Mnemonic:
    IGG A M
  • ABN:
    Not required
  • CPT Code:
    82784x3
  • LOINC Code:
    2465-3; 2458-8; 2472-9
  • Test Includes:
    28136 IgA, Quantitative, Serum
    28135 IgG, Quantitative, Serum
    28134 IgM, Quantitative, Serum
  • Also Known As:
    Immunoglobulins, Quantitative, Serum
    IgA, IgG, and IgM, Serum
    IgG, IgM, and IgA, Serum
    IgM, IgG, and IgA, Serum
  • Spec Type:
    Serum
  • Spec Container:
    Gold top (SST) or red top (serum) tube
  • Pref Vol:
    2.0 mL
  • Min Vol:
    1.0 mL
  • Fasting:
    No
  • Spec Collect:
    Routine venipuncture
  • Spec Process:
    Clot 30 minutes
    Promptly centrifuge 15 minutes
    Immediately transfer serum to separate plastic tube
    Properly centrifuged gel barrier tube sample does not require transfer of serum to separate tube
  • Spec Store Transport:
    Refrigerated
  • Spec Stability:
    8 hours room temperature (20-30°C)
    1 week refrigerated (2-8°C)
    If frozen within 24 hours of collection, 1 year frozen (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Methodology:
    Nephelometry
  • Use:
    Evaluate humoral immunity; evaluate monoclonal gammopathy; reach diagnosis of and monitor therapy in myeloma and macroglobulinemia of Waldenstrom and heavy chain disease; evaluate lymphoproliferative diseases, including lymphoma; evaluate patients with repeated infections (e.g., immune deficient states); evaluate primary biliary cirrhosis and other autoallergic liver disease, particularly chronic active hepatitis; evaluate amyloidosis
  • Clinical Significance:
    See individual tests – IgA, IgG, and IgM.
  • Reference Range:

    IgA, Quantitative, Serum
    0-12 months: 0-83 mg/dL
    1-3 years: 20-100 mg/dL
    4-6 years: 27-195 mg/dL
    7-9 years: 34-305 mg/dL
    10-11 years: 53-204 mg/dL
    12-13 years: 58-359 mg/dL
    14-15 years: 47-249 mg/dL
    16-19 years: 61-348 mg/dL
    ≥20 years: 70-400 mg/dL

    IgG, Quantitative, Serum
    0-12 months: 232-1411 mg/dL
    1-3 years: 453-916 mg/dL
    4-6 years: 504-1465 mg/dL
    7-9 years: 572-1474 mg/dL
    10-11 years: 698-1560 mg/dL
    12-13 years: 759-1550 mg/dL
    14-15 years: 716-1711 mg/dL
    16-19 years: 549-1584 mg/dL
    ≥20 years: 694-1619 mg/dL

    IgM, Quantitative, Serum
    0-12 months: 0-145 mg/dL
    1-3 years: 19-146 mg/dL
    4-6 years: 24-210 mg/dL
    7-9 years: 32-208 mg/dL
    10-11 years: 31-180 mg/dL
    12-13 years: 35-239 mg/dL
    14-15 years: 15-188 mg/dL
    16-19 years: 23-259 mg/dL
    20-60 years: 40-230 mg/dL
    ≥60 years: 30-360 mg/dL

  • Day Run:
    Mon, Wed, Fri
  • Time Run:
    8:00 am
  • Time Reported:
    5:00 pm
  • Test Type:
    IMMUNOLOGY

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