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Test Name:
Treponema pallidum, Reagin (RPR) Titer, Serum


  • SBMF No:
    28057
  • Performance Lab Name:
    Immunology
  • Test Mnemonic:
    STS QUANT
  • ABN:
    Not required
  • CPT Code:
    86593
  • LOINC Code:
    31147-2
  • Also Known As:
    STS Titer
    Serological Test for Syphilis
    Rapid Plasma Reagin
    RPR
    Non-Treponemal Syphilis Test
  • Spec Type:
    Serum
  • Spec Container:
    Gold top (SST) or red top (serum) tube
  • Alt Spec Type:
    Plasma
  • Alt Spec Container:
    Lavender top (EDTA) tube or green top (lithium heparin) tube
  • Pref Vol:
    1.0 mL
  • Min Vol:
    0.5 mL
  • Fasting:
    No
  • Spec Collect:
    Routine venipuncture
  • Spec Process:
    Serum sample tubes, clot 30 minutes
    Promptly centrifuge 15 minutes
    Immediately transfer serum or plasma to separate plastic tube
    Properly centrifuged gel barrier tube sample does not require transfer of serum to separate tube
  • Spec Store Transport:
    Refrigerated (48 hours plasma or 5 days serum)
  • Spec Stability:
    Serum:
    – 5 days refrigerated (2-8°C)
    – Greater than 5 days, freeze (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
    Plasma:
    – 48 hours refrigerated (2-8°C)
    – Frozen (-20°C): Unacceptable
  • Methodology:
    Flocculation
  • Use:
    Sensitive non-treponemal screening test for syphilis
    Monitor patient after treatment by titers detected by the quantitative test
  • Reference Range:
    Non-Reactive
  • Day Run:
    Mon-Fri
  • Time Run:
    6:00 am
  • Time Reported:
    5:00 pm
  • Test Type:
    INFECTIOUS ANTIBODY