SBMF Online Payment ▶

test directorySearch Results

Click here to search again.

Test Name:
Tissue Transglutaminase IgG Antibody


  • SBMF No:
    28054
  • Performance Lab Name:
    Immunology
  • Test Mnemonic:
    TTG IGG
  • ABN:
    Not required
  • CPT Code:
    83516
  • LOINC Code:
    32998-7
  • Also Known As:
    Anti-Human Tissue Transglutaminase (Hu-tTG) IgG Recombinant Antigen
    Human Tissue Transglutaminase IgG Antibody
    h-tTG IgG Ab
    Hu-tTG IgG Ab
    tTG IgG Ab
  • Also See:
    28014 Tissue Transglutaminase IgA Antibody
  • Spec Type:
    Serum
  • Spec Container:
    Gold top (SST) or red top (serum) tube
  • Pref Vol:
    0.5 mL
  • Min Vol:
    0.3 mL
  • Fasting:
    No
  • Spec Collect:
    Routine venipuncture
  • Spec Process:
    Clot 30 minutes
    Promptly centrifuge 15 minutes
    Immediately transfer serum to separate plastic tube
    Properly centrifuged gel barrier tube sample does not require transfer of serum to separate tube
  • Spec Store Transport:
    Refrigerated
  • Spec Stability:
    7 days refrigerated (2-8°C)
    Greater than 7 days, freeze (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Spec Reject:
    Severely lipemic, contaminated, or hemolyzed sample
  • Methodology:
    Enzyme-Linked Immunosorbent Assay (ELISA)
  • Use:
    Detection of IgG antibodies to tissue transglutaminase (endomysium), in conjunction with IgA antibodies, is an aid in diagnosis of certain gluten sensitive enteropathies such as celiac disease and dermatitis herpetiformis. This test is intended for providing added sensitivity when testing IgA deficient patients.
  • Clinical Significance:
    Celiac disease is a life-long condition in which the ingestion of gluten leads to chronic inflammation and damage of the small intestinal mucosa. Tissue transglutaminase has been identified as the major autoantigen in celiac disease. IgA antibodies against tTG are highly disease specific serological markers for celiac disease and dermatitis herpetiformis. tTG IgG antibodies are less specific for these diseases but are helpful markers in patients with IgA deficiency.
  • Reference Range:
    0.0-7.0 U/mL

    Interpretive Data:

    < 7.0
    7.0 - 10.0
    > 10.0    		U/mL = Negative
    U/mL = Equivocal
    U/mL = Positive

  • Day Run:
    Wed, Sat
  • Time Run:
    8:00 am
  • Time Reported:
    5:00 pm
  • Test Type:
    IMMUNOLOGY

Home > Test Directory > Search Results

Test Directory